IMPC phenotypes (gene matching)
C57BL/6N-Grm7em1H/H
| Status | Available to order |
| EMMA ID | EM:10779 |
| Citation information | RRID:IMSR_EM:10779 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Grm7em1H/H |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Grm7em1H |
| Gene/Transgene symbol | Grm7 |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6NTac males |
| Breeding at archiving centre | Maintained on a C57BL/6NTac background |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal recessive non-syndromic intellectual disability / Orphanet_88616
- Early infantile epileptic encephalopathy / Orphanet_1934
MGI phenotypes (gene matching)
- convulsive seizures / MGI
- impaired coordination / MGI
- abnormal contextual conditioning behavior / MGI
- seizures / MGI
- hyperresponsive to tactile stimuli / MGI
- abnormal conditioned taste aversion behavior / MGI
- increased susceptibility to pharmacologically induced seizures / MGI
- abnormal excitatory postsynaptic currents / MGI
- nervous system phenotype / MGI
- abnormal spatial working memory / MGI
- increased sensitivity to xenobiotic induced morbidity/mortality / MGI