C57BL/6NTac-Abcc5em1(IMPC)H/H
Status | Available to order |
EMMA ID | EM:10761 |
International strain name | C57BL/6NTac-Abcc5em1(IMPC)H/H |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Abcc5em1(IMPC)H |
Gene/Transgene symbol | Abcc5 |
Information from provider
Provider | MRC, Medical Research Council |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References |
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Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Animals used for archiving | heterozygous C57BL/6NTac |
Breeding at archiving centre | Maintained on a C57BL/6NTac background |
Disease and phenotype information
IMPC phenotypes (allele matching)
Literature references
- Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP-1.;Cyranka Malgorzata, Veprik Anna, McKay Eleanor J, van Loon Nienke, Thijsse Amber, Cotter Luke, Hare Nisha, Saibudeen Affan, Lingam Swathi, Pires Elisabete, Larraufie Pierre, Reimann Frank, Gribble Fiona, Stewart Michelle, Bentley Elizabeth, Lear Pamela, McCullagh James, Cantley James, Cox Roger D, de Wet Heidi, ;2019;Obesity (Silver Spring, Md.);27;1292-1304; 31338999
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