STOCK Arpc2tm1c(EUCOMM)Wtsi/WtsiBiat

Status

Available to order

EMMA IDEM:10742
International strain nameSTOCK Arpc2tm1c(EUCOMM)Wtsi/WtsiBiat
Alternative nameB6Dnk;B6Brd;B6N-Tyr Arpc2/WtsiBiat
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolArpc2tm1c(EUCOMM)Wtsi
Gene/Transgene symbolArpc2

Information from provider

ProviderThomas Ruelicke
Provider affiliationDepartment 1 (Biomedical Sciences), University of Veterinary Medicine, Vienna
Genetic informationThis line originates from EUCOMM ES clone EPD0058_1_D07, after breeding with a flp recombinase deleter line to convert the original targeted tm1a allele (knock-out first allele) into a conditional tm1c allele. For further details see the relevant page on the IMPC portal.
Phenotypic informationHomozygous:
no phenotype known

Heterozygous:
no phenotype known
Breeding historyThe tm1a mutant was crossed 2 times with CAG-FLPe mice, and the resulting offspring once with C57BL/6N mice. Backcrossed: 1 generation to C57BL/6N.
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreUniversity of Veterinary Medicine, Vienna, Austria

Disease and phenotype information

IMPC phenotypes (gene matching)
  • increased mean corpuscular hemoglobin / IMPC
  • abnormal coat/hair pigmentation / IMPC
  • decreased body weight / IMPC
  • decreased total body fat amount / IMPC
  • preweaning lethality, complete penetrance / IMPC
  • increased leukocyte cell number / IMPC
  • vertebral fusion / IMPC
  • increased mean corpuscular volume / IMPC
MGI phenotypes (gene matching)
  • decreased body weight / MGI
  • abnormal coat/hair pigmentation / MGI
  • increased mean corpuscular hemoglobin / MGI
  • decreased total body fat amount / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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