- increased mean corpuscular hemoglobin / IMPC
- abnormal coat/hair pigmentation / IMPC
- decreased body weight / IMPC
- decreased total body fat amount / IMPC
- preweaning lethality, complete penetrance / IMPC
- increased leukocyte cell number / IMPC
- vertebral fusion / IMPC
- increased mean corpuscular volume / IMPC
STOCK Arpc2tm1c(EUCOMM)Wtsi/WtsiBiat
Status | Available to order |
EMMA ID | EM:10742 |
International strain name | STOCK Arpc2tm1c(EUCOMM)Wtsi/WtsiBiat |
Alternative name | B6Dnk;B6Brd;B6N-Tyr |
Strain type | Targeted Mutant Strains : Conditional mutation |
Allele/Transgene symbol | Arpc2tm1c(EUCOMM)Wtsi |
Gene/Transgene symbol | Arpc2 |
Information from provider
Provider | Thomas Ruelicke |
Provider affiliation | Department 1 (Biomedical Sciences), University of Veterinary Medicine, Vienna |
Genetic information | This line originates from EUCOMM ES clone EPD0058_1_D07, after breeding with a flp recombinase deleter line to convert the original targeted tm1a allele (knock-out first allele) into a conditional tm1c allele. For further details see the relevant page on the IMPC portal. |
Phenotypic information | Homozygous:no phenotype knownHeterozygous:no phenotype known |
Breeding history | The tm1a mutant was crossed 2 times with CAG-FLPe mice, and the resulting offspring once with C57BL/6N mice. Backcrossed: 1 generation to C57BL/6N. |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | University of Veterinary Medicine, Vienna, Austria |
Disease and phenotype information
IMPC phenotypes (gene matching)
Information on how we integrate external resources can be found here
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).