B6.129P2-Dp(16Lipi-Hunk)9TybEmcf/TybH
| Status | Available to order |
| EMMA ID | EM:10565 |
| International strain name | B6.129P2-Dp(16Lipi-Hunk)9TybEmcf/TybH |
| Alternative name | Dp9Tyb |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Dp(16Lipi-Hunk)9TybEmcf |
| Gene/Transgene symbol | Dp(16Lipi-Hunk)9TybEmcf |
Information from provider
| Provider | Victor Tybulewicz |
| Provider affiliation | Francis Crick Institute |
| Additional owner | Elzabethe Fisher, University College London, UK |
| Genetic information | Duplication of 15.6Mb of Mmu16 from Lipi to Hunk |
| Phenotypic information | Homozygous:UnknownHeterozygous:No phenotype found. |
| Breeding history | Mutation made in HM-1 ES cells, transmitted through the germline and maintained by backcrossing to C57BL/6J |
| References |
|
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6 |
| Breeding at archiving centre | C57BL/6J |
Literature references
- Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel.;Lana-Elola Eva, Watson-Scales Sheona, Slender Amy, Gibbins Dorota, Martineau Alexandrine, Douglas Charlotte, Mohun Timothy, Fisher Elizabeth Mc, Tybulewicz Victor Lj, ;2016;eLife;5;1165-1186; 26765563
- Rodent models in Down syndrome research: impact and future opportunities.;Herault Yann, Delabar Jean M, Fisher Elizabeth M C, Tybulewicz Victor L J, Yu Eugene, Brault Veronique, ;2017;Disease models & mechanisms;10;; 28993310