B6.129P2-Dp(16Lipi-Hunk)9TybEmcf/TybH

Status	Available to order
EMMA ID	EM:10565
Citation information	RRID:IMSR_EM:10565 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	B6.129P2-Dp(16Lipi-Hunk)9TybEmcf/TybH
Alternative name	Dp9Tyb
Strain type	Targeted Mutant Strains : Other targeted
Allele/Transgene symbol	Dp(16Lipi-Hunk)9TybEmcf
Gene/Transgene symbol	Dp(16Lipi-Hunk)9TybEmcf

Information from provider

Provider	Victor Tybulewicz
Provider affiliation	Francis Crick Institute
Additional owner	Elzabethe Fisher, University College London, UK
Genetic information	Duplication of 15.6Mb of Mmu16 from Lipi to Hunk
Phenotypic information	Homozygous: Unknown Heterozygous: No phenotype found.
Breeding history	Mutation made in HM-1 ES cells, transmitted through the germline and maintained by backcrossing to C57BL/6J
References	Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel.;Lana-Elola Eva, Watson-Scales Sheona, Slender Amy, Gibbins Dorota, Martineau Alexandrine, Douglas Charlotte, Mohun Timothy, Fisher Elizabeth Mc, Tybulewicz Victor Lj, ;2016;eLife;5;1165-1186; 26765563 Rodent models in Down syndrome research: impact and future opportunities.;Herault Yann, Delabar Jean M, Fisher Elizabeth M C, Tybulewicz Victor L J, Yu Eugene, Brault Veronique, ;2017;Disease models & mechanisms;10;; 28993310
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom
Animals used for archiving	heterozygous C57BL/6 males
Breeding at archiving centre	C57BL/6J

Literature references

Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel.;Lana-Elola Eva, Watson-Scales Sheona, Slender Amy, Gibbins Dorota, Martineau Alexandrine, Douglas Charlotte, Mohun Timothy, Fisher Elizabeth Mc, Tybulewicz Victor Lj, ;2016;eLife;5;1165-1186; 26765563
Rodent models in Down syndrome research: impact and future opportunities.;Herault Yann, Delabar Jean M, Fisher Elizabeth M C, Tybulewicz Victor L J, Yu Eugene, Brault Veronique, ;2017;Disease models & mechanisms;10;; 28993310

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*
Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

Not found what you were looking for? Search here for other strains available from EMMA.