C57BL/6N-Arid1btm1a(EUCOMM)Hmgu/Cnbc

Status

Available to order

EMMA IDEM:10411
International strain nameC57BL/6N-Arid1btm1a(EUCOMM)Hmgu/Cnbc
Alternative nameC57BL/6N-Arid1b/Cnbc
Strain typeTargeted Mutant Strains
Allele/Transgene symbolArid1btm1a(EUCOMM)Hmgu
Gene/Transgene symbolArid1b

Information from provider

ProviderPedro Medina
Provider affiliationPfizer - Junta de Andalucia - Universidad de Granada, Center for Genomics and Ontology Reseach (GenyO)
Genetic informationThis mouse line originates from EUCOMM ES clone HEPD0532_6_A11.
Phenotypic informationHomozygous:
Potential phenotyping data in the IMPC portal

Heterozygous:
See above
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreCNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain
Animals used for archivingheterozygous C57BL/6N

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (gene matching)
  • abnormal spleen morphology / IMPC
  • decreased prepulse inhibition / IMPC
  • preweaning lethality, complete penetrance / IMPC
  • decreased locomotor activity / IMPC
  • impaired cued conditioning behavior / IMPC
  • edema / IMPC
  • male infertility / IMPC
  • increased circulating creatinine level / IMPC
  • increased freezing behavior / IMPC
  • abnormal freezing behavior / IMPC
  • decreased exploration in new environment / IMPC
  • decreased fasting circulating glucose level / IMPC
  • preweaning lethality, incomplete penetrance / IMPC
MGI phenotypes (gene matching)
  • muscle weakness / MGI
  • decreased corpus callosum size / MGI
  • abnormal dentate gyrus morphology / MGI
  • decreased body length / MGI
  • decreased body weight / MGI
  • decreased body size / MGI
  • increased anxiety-related response / MGI
  • increased grooming behavior / MGI
  • abnormal vocalization / MGI
  • postnatal growth retardation / MGI
  • abnormal homeostasis / MGI
  • hydroencephaly / MGI
  • small heart / MGI
  • decreased heart weight / MGI
  • small kidney / MGI
  • decreased kidney weight / MGI
  • decreased circulating insulin-like growth factor I level / MGI
  • behavior/neurological phenotype / MGI
  • abnormal hypothalamus physiology / MGI
  • thin cerebral cortex / MGI
  • abnormal insulin-like growth factor I level / MGI
  • decreased neuron number / MGI
  • decreased birth body size / MGI
  • decreased grip strength / MGI
  • perinatal lethality, complete penetrance / MGI
  • decreased dentate gyrus size / MGI
  • abnormal response to social novelty / MGI
  • decreased cerebral cortex cell number / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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