C57BL/6N-Cryba1tm1(EGFP/cre/ERT2)Wtsi/Cnrm
| Status | Available to order |
| EMMA ID | EM:10213 |
| International strain name | C57BL/6N-Cryba1tm1(EGFP/cre/ERT2)Wtsi/Cnrm |
| Alternative name | CEPD0105_3_B04 |
| Strain type | |
| Allele/Transgene symbol | Cryba1tm1(EGFP/cre/ERT2)Wtsi |
| Gene/Transgene symbol | Cryba1 |
Information from provider
| Provider | CNR, Consiglio Nazionale delle Ricerche |
| Provider affiliation | EMMA-Monterotondo Campus International Development, CNR, Consiglio Nazionale delle Ricerche |
| Genetic information | This mouse line originates from EUCOMM ES clone CEPD0105_3_B04. For further details on the construction of this clone see the page at the IMPC portal. Quality Control/Disclaimer: The structure of the targeted mutation is not fully verified. It is recommended that the recipient confirms the mutation structure by Southern blotting. The Cre expression pattern is expected to mirror that of the host gene, but this may not be fully described and/or may be modified in the targeted allele. Although characterisation of the Cre expression pattern is an objective of EUCOMMTools this is an ongoing process which may be incomplete. It is therefore recommended that the recipient verifies the Cre expression pattern. For the tm1(EGFP/Cre/ERT2) type allele, if the promoter-driven selection cassette is flanked with Rox sites, it may be removed using Dre recombinase. Please be aware that the strain description may be subject to change. For the most recent description please consult the information pages for the appropriate product details at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Early-onset sutural cataract / Orphanet_98985
- Early-onset posterior polar cataract / Orphanet_98993
- Early-onset lamellar cataract / Orphanet_441452
- Early-onset nuclear cataract / Orphanet_98991