B6.Cg-Zbed6tm1.1.Sson/Kctt

Status

Available to order

EMMA IDEM:10027
International strain nameB6.Cg-Zbed6tm1.1.Sson/Kctt
Alternative nameZbed6 floxed
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolZbed6tm1.1Sson
Gene/Transgene symbolZbed6

Information from provider

ProviderLeif Andersson
Provider affiliationDepartment of Medical Biochemistry and Microbiology, Uppsala University
Genetic informationConditional knock-out model for the Zbed6 gene (flanked by loxP sites).
Phenotypic informationHomozygous:
Indication of higher weight in homozygous KO mice compared to heterozygotes and wild-type.

Heterozygous:
Indication of higher weight in heterozygous mice compared to wild-type.
ReferencesNone available
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreKarolinska Institutet, Stockholm, Sweden
Animals used for archivinghomozygous C57BL/6J

Disease and phenotype information

IMPC phenotypes (gene matching)
  • prolonged RR interval / IMPC
  • preweaning lethality, incomplete penetrance / IMPC
  • decreased heart rate / IMPC
MGI phenotypes (gene matching)
  • increased body weight / MGI
  • increased insulin sensitivity / MGI
  • increased liver weight / MGI
  • increased skeletal muscle size / MGI
  • increased kidney weight / MGI
  • increased lean body mass / MGI
  • increased respiratory quotient / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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