IMPC phenotypes (gene matching)
C57BL/6N-Jarid2tm2(EGFP/cre/ERT2)Wtsi/Cnrm
| Status | Available to order |
| EMMA ID | EM:10018 |
| International strain name | C57BL/6N-Jarid2tm2(EGFP/cre/ERT2)Wtsi/Cnrm |
| Alternative name | CEPD0096_1_A05 |
| Strain type | |
| Allele/Transgene symbol | Jarid2tm2(EGFP/cre/ERT2)Wtsi |
| Gene/Transgene symbol | Jarid2 |
Information from provider
| Provider | CNR, Consiglio Nazionale delle Ricerche |
| Provider affiliation | EMMA-Monterotondo Campus International Development, CNR, Consiglio Nazionale delle Ricerche |
| Genetic information | This mouse line originates from EUCOMM ES clone CEPD0096_1_A05. For further details on the construction of this clone see the page at the IMPC portal. Quality Control/Disclaimer: The structure of the targeted mutation is not fully verified. It is recommended that the recipient confirms the mutation structure by Southern blotting. The Cre expression pattern is expected to mirror that of the host gene, but this may not be fully described and/or may be modified in the targeted allele. Although characterisation of the Cre expression pattern is an objective of EUCOMMTools this is an ongoing process which may be incomplete. It is therefore recommended that the recipient verifies the Cre expression pattern. For the tm2(EGFP/Cre/ERT2) type allele, if the promoter-driven selection cassette is flanked with Rox sites, it may be removed using Dre recombinase. Please be aware that the strain description may be subject to change. For the most recent description please consult the information pages for the appropriate product details at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Non-specific syndromic intellectual disability / Orphanet_528084
MGI phenotypes (gene matching)
- abnormal sternum morphology / MGI
- abnormal erythropoiesis / MGI
- abnormal heart development / MGI
- abnormal myocardial fiber morphology / MGI
- abnormal interventricular septum morphology / MGI
- double outlet right ventricle / MGI
- distended pericardium / MGI
- trabecula carnea hypoplasia / MGI
- abnormal liver morphology / MGI
- liver hypoplasia / MGI
- small liver / MGI
- enlarged liver sinusoidal spaces / MGI
- decreased hepatocyte number / MGI
- abnormal liver physiology / MGI
- spleen hypoplasia / MGI
- incomplete rostral neuropore closure / MGI
- anemia / MGI
- hepatic necrosis / MGI
- decreased embryo size / MGI
- edema / MGI
- thymus hypoplasia / MGI
- hemorrhage / MGI
- respiratory failure / MGI
- prenatal lethality / MGI
- abnormal definitive hematopoiesis / MGI
- abnormal neural tube morphology / MGI
- abnormal myocardial trabeculae morphology / MGI
- abnormal megakaryocyte progenitor cell morphology / MGI
- delayed neural tube closure / MGI
- thin myocardium / MGI
- abnormal fetal cardiomyocyte proliferation / MGI
- nervous system phenotype / MGI
- abnormal neural tube closure / MGI
- abnormal nervous system development / MGI
- abnormal heart left ventricle morphology / MGI
- abnormal interventricular groove morphology / MGI
- abnormal myocardium compact layer morphology / MGI
- dilated heart right atrium / MGI
- fetal growth retardation / MGI
- abnormal thoracic cage morphology / MGI
- abnormal neural fold formation / MGI
- abnormal myocardium layer morphology / MGI
- increased circulating creatinine level / MGI
- abnormal neural plate morphology / MGI
- abnormal splenic cell ratio / MGI
- abnormal thymus cell ratio / MGI
- ventricular septal defect / MGI
- abnormal coronary vessel morphology / MGI
- perinatal lethality, complete penetrance / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- lethality throughout fetal growth and development, complete penetrance / MGI
- embryonic lethality during organogenesis, incomplete penetrance / MGI
- lethality throughout fetal growth and development, incomplete penetrance / MGI
- decreased fetal derived definitive erythrocyte cell number / MGI