STOCK Ralbtm1.2Cjm/H

Status

Available to order

EMMA IDEM:10003
International strain nameSTOCK Ralbtm1.2Cjm/H
Alternative nameRalB
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolRalbtm1.2Cjm
Gene/Transgene symbolRalb

Information from provider

ProviderAfshan McCarthy
Provider affiliationCancer Biology, Institute of Cancer Research
Genetic informationConditional targeting of RalB gene.
Phenotypic informationHomozygous:
Homozygous mice are fertile and have a normal lifespan.

Heterozygous:
Heterozygous mice are fertile and have a normal lifespan.
References
  • Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis.;Peschard Pascal, McCarthy Afshan, Leblanc-Dominguez Valérie, Yeo Maggie, Guichard Sabrina, Stamp Gordon, Marshall Christopher J, ;2012;Current biology : CB;22;2063-8; 23063435
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom
Animals used for archivinghomozygous C57BL/6J
Breeding at archiving centreNo additional breeding was done at the repository

Disease and phenotype information

IMPC phenotypes (gene matching)
  • increased leukocyte cell number / IMPC
  • abnormal vertebral arch morphology / IMPC
MGI phenotypes (gene matching)
  • no abnormal phenotype detected / MGI

Literature references

  • Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis.;Peschard Pascal, McCarthy Afshan, Leblanc-Dominguez Valérie, Yeo Maggie, Guichard Sabrina, Stamp Gordon, Marshall Christopher J, ;2012;Current biology : CB;22;2063-8; 23063435

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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