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"code_internal":"ApoE/PLGN", "_version_":1837343093279424512 },{ "id_str":"9938", "name_str":"B6N.Cg-Stat1 Gt(ROSA)26Sor Col1a1/Biat", "gene_symbol":"Stat1", "do_id":["DOID:0080600"], "do_term":["COVID-19"], "mp_term":["increased white adipose tissue amount","abnormal adipose tissue distribution","abnormal ear pigmentation","big ears","thick ears","abnormal malleus morphology","abnormal cochlea morphology","abnormal otic capsule morphology","abnormal organ of Corti morphology","delayed bone ossification","fragile skeleton","increased bone mineral density","decreased bone mineral density","failure of bone resorption","abnormal bone marrow cavity morphology","osteopetrosis","kyphoscoliosis","axial skeleton hypoplasia","abnormal neurocranium morphology","absent mandible","short mandible","short maxilla","abnormal frontal bone morphology","abnormal parietal bone morphology","cleft palate","abnormal trabecular bone morphology","abnormal long bone metaphysis morphology","decreased compact bone thickness","abnormal vertebrae morphology","abnormal vertebral body morphology","abnormal rib morphology","rib fusion","kyphosis","scoliosis","abnormal cartilage morphology","abnormal cartilage development","abnormal long bone hypertrophic chondrocyte zone","abnormal chondrocyte morphology","abnormal bone marrow cell number","decreased circulating LDL cholesterol level","abnormal circulating glucose level","hypoglycemia","decreased hematocrit","absent erythroid progenitor cell","increased leukocyte cell number","increased neutrophil cell number","increased monocyte cell number","decreased leukocyte cell number","decreased neutrophil cell number","decreased monocyte cell number","abnormal megakaryocyte differentiation","absent pre-B cells","extramedullary hematopoiesis","abnormal erythropoiesis","macrocytosis","abnormal blood vessel physiology","vasculature congestion","abnormal vascular development","abnormal angiogenesis","abnormal heart morphology","abnormal heart development","abnormal aorta morphology","enlarged heart","heart right ventricle hypertrophy","abnormal myocardial fiber morphology","thin ventricular wall","double outlet right ventricle","abnormal heart valve morphology","abnormal atrioventricular cushion morphology","absent atrioventricular cushions","decreased atrioventricular cushion size","abnormal cell death","cellular necrosis","increased bone marrow cell number","increased granulocyte number","decreased bone marrow cell number","decreased granulocyte number","altered response to myocardial infarction","abnormal cell proliferation","increased cell proliferation","decreased cell proliferation","abnormal cell morphology","abnormal vascular regression","diluted coat color","belly spot","abnormal hair follicle morphology","absent hair follicles","decreased hair follicle number","abnormal awl hair morphology","abnormal zigzag hair morphology","abnormal auchene hair morphology","excessive hair","polyphalangy","alopecia","sparse hair","focal hair loss","ruffled hair","delayed hair regrowth","retarded hair growth","abnormal hair cycle","abnormal craniofacial morphology","abnormal cranium morphology","domed cranium","short snout","abnormal maxilla morphology","abnormal mandible morphology","abnormal digestive system morphology","gastrointestinal hemorrhage","abnormal esophageal epithelium morphology","abnormal stomach epithelium morphology","abnormal stomach glandular epithelium morphology","abnormal intestine morphology","abnormal enterocyte morphology","increased rib number","abnormal pulmonary artery morphology","abnormal intestinal epithelium morphology","abnormal large intestine morphology","abnormal crypts of Lieberkuhn morphology","rectal prolapse","abnormal cecum morphology","abnormal colon morphology","abnormal small intestine morphology","abnormal intestinal mucosa morphology","abnormal renal/urinary system morphology","hydronephrosis","absent kidney","abnormal kidney development","delayed kidney development","abnormal kidney blood vessel morphology","short limbs","abnormal forelimb morphology","absent forelimb","abnormal hindlimb morphology","absent hindlimb","abnormal tibia morphology","abnormal femur morphology","polydactyly","syndactyly","oligodactyly","interdigital webbing","abnormal autopod morphology","abnormal foot pad morphology","increased foot pad pigmentation","ulcerated paws","kinked tail","thin tail","abnormal liver development","abnormal liver morphology","enlarged liver","liver hypoplasia","enlarged liver sinusoidal spaces","decreased hepatocyte number","abnormal hepatocyte morphology","abnormal mammary gland development","mammary gland hyperplasia","pituitary gland hyperplasia","sebaceous gland atrophy","abnormal sex gland morphology","prostate gland hyperplasia","abnormal branching of the mammary ductal tree","abnormal immune system morphology","abnormal spleen morphology","enlarged spleen","small spleen","spleen hyperplasia","spleen hypoplasia","abnormal Peyer's patch morphology","enlarged lymph nodes","abnormal thymus morphology","abnormal thymus development","athymia","small thymus","thymus hyperplasia","enlarged thymus","decreased thymocyte number","abnormal lymphocyte cell number","abnormal myogenesis","abnormal muscle development","tremors","weakness","muscle weakness","muscle degeneration","abnormal muscle regeneration","myopathy","dystrophic muscle","paresis","hindlimb paralysis","abnormal skeletal muscle morphology","abnormal tongue morphology","abnormal tongue epithelium morphology","abnormal forebrain morphology","telencephalon hypoplasia","abnormal cerebral cortex morphology","thickened cerebral cortex","abnormal stratification in cerebral cortex","abnormal dentate gyrus morphology","abnormal brain ventricle morphology","abnormal thalamus morphology","abnormal hindbrain morphology","abnormal pons morphology","abnormal cerebellum morphology","small cerebellum","abnormal cerebellum development","abnormal cerebellar foliation","abnormal somatosensory cortex morphology","abnormal cerebellum vermis morphology","cerebellum vermis hypoplasia","decreased anterior vermis size","abnormal cerebellum posterior vermis morphology","abnormal cerebellum external granule cell layer morphology","thin external granule cell layer","irregular external granule cell layer thickness","Purkinje cell degeneration","abnormal Purkinje cell morphology","decreased Purkinje cell number","abnormal midbrain morphology","abnormal superior colliculus morphology","abnormal brain development","exencephaly","abnormal myelination","demyelination","open neural tube","absent notochord","abnormal rhombomere morphology","abnormal telencephalon development","abnormal motor neuron morphology","motor neuron degeneration","decreased motor neuron number","abnormal seizure response to pharmacological agent","abnormal oligodendrocyte morphology","decreased oligodendrocyte progenitor number","abnormal spinal cord morphology","abnormal somatic sensory system morphology","abnormal dorsal root ganglion morphology","fused dorsal root ganglion","decreased sensory neuron number","abnormal sensory neuron innervation pattern","abnormal olfactory receptor morphology","abnormal retinal photoreceptor morphology","abnormal retinal cone cell morphology","abnormal sympathetic ganglion morphology","abnormal sympathetic neuron morphology","abnormal parasympathetic ganglion morphology","abnormal enteric ganglia morphology","abnormal neuromuscular synapse morphology","abnormal trigeminal nerve morphology","abnormal facial nerve morphology","abnormal vestibulocochlear nerve morphology","abnormal hypoglossal nerve morphology","abnormal cranial ganglia morphology","abnormal geniculate ganglion morphology","abnormal trigeminal ganglion morphology","small trigeminal ganglion","abnormal glossopharyngeal ganglion morphology","abnormal vagus ganglion morphology","abnormal Schwann cell morphology","abnormal uterus morphology","abnormal ovary morphology","small ovary","abnormal ovarian follicle morphology","small testis","arrest of spermatogenesis","abnormal prostate gland morphology","abnormal lung morphology","abnormal lung development","pulmonary hypoplasia","thick pulmonary interalveolar septum","lung hemorrhage","overexpanded pulmonary alveoli","pigmentation phenotype","hyperpigmentation","reddish skin","abnormal skin condition","scaly skin","dermatitis","tight skin","thick skin","wrinkled skin","skin lesions","skin hyperplasia","abnormal epidermal layer morphology","thin epidermis","thick epidermis","epidermal hyperplasia","hyperkeratosis","abnormal dermal layer morphology","thick dermal layer","dermal cysts","increased body length","decreased body length","increased body weight","decreased body weight","weight loss","increased body size","decreased body size","distended abdomen","increased metastatic potential","decreased metastatic potential","abnormal eye development","anophthalmia","microphthalmia","abnormal eye distance/ position","cataract","fused cornea and lens","abnormal cornea morphology","abnormal eye pigmentation","abnormal retina morphology","retinal degeneration","decreased retinal photoreceptor cell number","disorganized retinal layers","abnormal optic nerve morphology","abnormal optic nerve innervation","absent optic nerve","abnormal eyelid morphology","absent eyelids","increased anxiety-related response","decreased anxiety-related response","abnormal tail movements","abnormal locomotor behavior","ataxia","circling","hyperactivity","hypoactivity","impaired coordination","abnormal gait","short stride length","increased exploration in new environment","dehydration","abnormal eating behavior","polyphagia","reduced long term potentiation","unresponsive to tactile stimuli","abnormal posture","hunched posture","abnormal coat appearance","disheveled coat","limb grasping","abnormal motor coordination/balance","impaired righting response","impaired balance","abnormal osteoclast physiology","abnormal cardiovascular system physiology","abnormal hematopoietic system physiology","abnormal lipid level","increased circulating triglyceride level","increased circulating free fatty acid level","increased circulating HDL cholesterol level","hyperglycemia","abnormal circulating enzyme level","anemia","abnormal myelopoiesis","impaired myelopoiesis","impaired hematopoiesis","abnormal blood vessel morphology","abnormal vasculogenesis","cardiac hypertrophy","internal hemorrhage","irregular heartbeat","multifocal hepatic necrosis","abnormal digestive system physiology","abnormal digestion","abnormal intestinal absorption","abnormal embryo development","abnormal germ layer development","abnormal mesoderm development","absent mesoderm","abnormal endoderm development","abnormal somite development","failure of somite differentiation","failure of primitive streak formation","failure to gastrulate","decreased embryo size","abnormal embryo turning","abnormal placenta morphology","decreased trophoblast giant cell number","abnormal placenta labyrinth morphology","abnormal visceral yolk sac morphology","absent vitelline blood vessels","pale yolk sac","impaired embryo implantation","embryonic growth arrest","postnatal growth retardation","polyuria","abnormal homeostasis","abnormal body temperature homeostasis","edema","abnormal immune system physiology","impaired wound healing","abnormal humoral immune response","arrested B cell differentiation","decreased IgG level","decreased IgM level","decreased IgA level","thymus hypoplasia","abnormal thymus involution","arrested T cell differentiation","abnormal T cell activation","increased activated T cell number","decreased level of surface class I molecules","autoimmune response","abnormal inflammatory response","increased inflammatory response","brain inflammation","conjunctivitis","heart inflammation","intestinal inflammation","kidney inflammation","liver inflammation","lung inflammation","sinus inflammation","stomach inflammation","decreased inflammatory response","abnormal lymphatic vessel morphology","increased mammary adenocarcinoma incidence","mammary gland alveolar hyperplasia","delayed brain development","hydroencephaly","hemorrhage","intracranial hemorrhage","abnormal reproductive system physiology","reduced fertility","reduced male fertility","reduced female fertility","infertility","male infertility","female infertility","abnormal estrous cycle","increased litter size","decreased litter size","delayed sexual maturation","abnormal pancreas morphology","abnormal mucociliary clearance","abnormal breathing pattern","respiratory distress","hypopnea","emphysema","deafness","abnormal pain threshold","increased thermal nociceptive threshold","neoplasm","increased cellular sensitivity to gamma-irradiation","preneoplasia","increased papilloma incidence","increased malignant tumor incidence","increased tumor incidence","increased incidence of induced tumors","increased B cell derived lymphoma incidence","increased T cell derived lymphoma incidence","increased leukemia incidence","increased lung adenocarcinoma incidence","increased sarcoma incidence","increased rhabdomyosarcoma incidence","increased carcinoma incidence","increased neuroblastoma incidence","increased lung adenoma incidence","increased pheochromocytoma incidence","increased skin papilloma incidence","decreased tumor incidence","neonatal lethality","abnormal skin morphology","seizures","abnormal motor capabilities/coordination/movement","abnormal sensory capabilities/reflexes/nociception","abnormal hair growth","abnormal coat/hair pigmentation","abnormal glucose homeostasis","increased circulating insulin level","prenatal lethality","perinatal lethality","postnatal lethality","premature death","abnormal embryonic tissue morphology","abnormal extraembryonic tissue morphology","abnormal eye morphology","abnormal skin pigmentation","abnormal ear morphology","abnormal muscle morphology","abnormal limb morphology","abnormal digit morphology","abnormal tail morphology","abnormal skeleton development","abnormal axial skeleton morphology","abnormal limb bone morphology","abnormal craniofacial bone morphology","abnormal lipid homeostasis","abnormal definitive hematopoiesis","abnormal blood circulation","abnormal respiratory system physiology","abnormal kidney morphology","abnormal kidney physiology","abnormal B cell differentiation","abnormal T cell differentiation","abnormal neural tube morphology","abnormal brain morphology","abnormal fertility/fecundity","altered tumor susceptibility","no abnormal phenotype detected","decreased brain weight","increased brain weight","abnormal astrocyte morphology","gliosis","abnormal innervation","abnormal fibula morphology","small heart","abnormal artery morphology","hydrops fetalis","abnormal CNS synaptic transmission","abnormal seminiferous tubule morphology","small lymph nodes","neurodegeneration","abnormal turbinate morphology","abnormal pulmonary alveolus morphology","abnormal nervous system electrophysiology","abnormal diaphragm morphology","abnormal respiratory mucosa goblet cell morphology","decreased susceptibility to hepatic steatosis","abnormal blood gas level","abnormal lymph node B cell domain morphology","abnormal lymph node T cell domain morphology","abnormal spleen white pulp morphology","abnormal spleen marginal zone morphology","abnormal thymus lobule morphology","abnormal Peyer's patch germinal center morphology","abnormal hematopoietic system morphology/development","abnormal bone marrow morphology","abnormal bone marrow cell morphology/development","abnormal lymphopoiesis","increased intestinal adenoma incidence","increased susceptibility to infection","abnormal double-negative T cell morphology","increased susceptibility to bacterial infection","abnormal megakaryocyte progenitor cell morphology","abnormal proerythroblast morphology","abnormal megakaryocyte morphology","increased susceptibility to viral infection","disproportionate dwarf","abnormal semicircular canal morphology","abnormal blood cell morphology/development","abnormal CD4-positive","alpha beta T cell morphology","abnormal effector T cell morphology","abnormal granulocyte morphology","abnormal leukocyte physiology","abnormal T cell physiology","abnormal erythrocyte morphology","abnormal macrophage physiology","abnormal professional antigen presenting cell physiology","abnormal B cell physiology","abnormal neutrophil physiology","abnormal immunoglobulin level","decreased IgE level","increased IgG level","increased IgM level","increased IgA level","increased IgE level","brachydactyly","increased mean corpuscular volume","decreased mean corpuscular volume","increased mean platelet volume","increased basophil cell number","increased hematocrit","abnormal lymphocyte morphology","hepatic steatosis","abnormal epididymis morphology","vestigial tail","persistent truncus arteriosis","delayed vaginal opening","reticulocytosis","anisopoikilocytosis","abnormal sciatic nerve morphology","abnormal keratinocyte morphology","abnormal keratinocyte differentiation","chondrodystrophy","decreased circulating corticosterone level","asthenozoospermia","uterus hyperplasia","oligozoospermia","abnormal pancreas physiology","abnormal circulating glucagon level","decreased circulating glucagon level","abnormal vitreous body morphology","abnormal renal tubule morphology","dilated renal tubules","decreased glucagon secretion","increased circulating glucagon level","abnormal inner cell mass morphology","abnormal immune system organ morphology","abnormal vein morphology","decreased circulating insulin level","abnormal mechanical nociception","abnormal chemical nociception","heart hypoplasia","glomerulonephritis","abnormal semilunar valve morphology","exophthalmos","dilated heart left ventricle","decreased vertical activity","ectopic cerebellar granule cells","short tibia","short fibula","small adrenal glands","decreased circulating testosterone level","abnormal retinal vasculature morphology","dilated cardiomyopathy","impaired skin barrier function","increased thigmotaxis","abnormal long term object recognition memory","colitis","abnormal dental pulp cavity morphology","abnormal notochord morphology","coarse hair","increased heart weight","abnormal lens fiber morphology","impaired skeletal muscle contractility","abnormal cochlear ganglion morphology","cochlear ganglion degeneration","abnormal ocular fundus morphology","increased growth rate","albuminuria","polycythemia","decreased hemoglobin content","decreased erythrocyte cell number","abnormal melanocyte morphology","abnormal neuron morphology","abnormal pharyngeal arch morphology","abnormal glutamate-mediated receptor currents","increased insulin sensitivity","abnormal bone mineralization","decreased urine phosphate level","increased circulating parathyroid hormone level","delayed wound healing","abnormal excitatory postsynaptic currents","aganglionic megacolon","abnormal bile duct morphology","abnormal bile duct development","joint inflammation","joint swelling","white spotting","increased circulating alanine transaminase level","decreased circulating alanine transaminase level","increased lactate dehydrogenase level","abnormal inhibitory postsynaptic currents","increased hemangioma incidence","abnormal neural crest cell migration","increased intestinal adenocarcinoma incidence","increased urine protein level","increased circulating serum albumin level","decreased circulating alkaline phosphatase level","increased circulating alkaline phosphatase level","abnormal brown adipose tissue morphology","abnormal cardiac muscle contractility","vascular smooth muscle hypertrophy","increased liver weight","increased retinal ganglion cell number","decreased urine calcium level","small kidney","arthritis","primary sex reversal","abnormal bone healing","abnormal cytokine secretion","no phenotypic analysis","abnormal coronary flow rate","vertebral transformation","increased myocardial infarction size","decreased myocardial infarction size","hypoalgesia","liver cirrhosis","abnormal cervical vertebrae morphology","abnormal lumbar vertebrae morphology","omphalocele","spina bifida","abnormal long bone epiphyseal plate morphology","abnormal hyoid bone morphology","abnormal epicardium morphology","decreased insulin secretion","abnormal coping response","enlarged kidney","increased vascular permeability","decreased vascular permeability","abnormal metatarsal bone morphology","increased susceptibility to ischemic brain injury","abnormal cell cycle","abnormal soleus morphology","abnormal skeletal muscle fiber morphology","abnormal egg cylinder morphology","absent allantois","decreased skin tensile strength","abnormal cell migration","decreased corneal stroma thickness","decreased tendon stiffness","liver degeneration","short femur","abnormal cell nucleus morphology","abnormal digestive system development","hypospadia","persistent cloaca","anal atresia","increased erythrocyte cell number","increased erythroid progenitor cell number","patent ductus arteriosus","cardiac fibrosis","absent lateral semicircular canal","thrombocytopenia","abnormal redox activity","increased neuron apoptosis","testicular atrophy","decreased susceptibility to age related obesity","renal interstitial fibrosis","increased cardiomyocyte apoptosis","decreased cardiomyocyte apoptosis","abnormal vitelline vasculature morphology","abnormal dopaminergic neuron morphology","loss of dopaminergic neurons","loss of glutamate neurons","abnormal abdominal wall morphology","intestinal obstruction","abnormal duodenum morphology","aneurysm","intestinal edema","abnormal intestinal peristalsis","melena","gastric polyps","large intestinal inflammation","small intestinal inflammation","increased liver adenoma incidence","liver failure","amyloid beta deposits","increased hepatocellular carcinoma incidence","liver fibrosis","decreased pancreatic beta cell number","astrocytosis","hypaxial muscle hypoplasia","decreased cardiac output","abnormal embryonic hematopoiesis","increased muscle weight","increased skeletal muscle size","kinked neural tube","decreased liver weight","absent placental labyrinth","increased width of hypertrophic chondrocyte zone","decreased width of hypertrophic chondrocyte zone","hair follicle degeneration","epidermal cyst","premature intramembranous bone ossification","delayed endochondral bone ossification","premature neuronal precursor differentiation","abnormal optic vesicle formation","parakeratosis","renal hypoplasia","decreased tumor growth/size","abnormal tumor morphology","abnormal intestinal goblet cell morphology","enlarged pancreas","absent tail","abnormal single cell response","abnormal channel response","increased thyroid adenoma incidence","abnormal vagina development","osteoarthritis","abnormal pancreatic beta cell physiology","abnormal fetal cardiomyocyte proliferation","increased ovarian carcinoma incidence","increased fibroma incidence","ureter obstruction","epididymal inflammation","abnormal prostate gland physiology","nervous system phenotype","abnormal nervous system morphology","abnormal nervous system physiology","abnormal synaptic transmission","small lung","spleen atrophy","thymus atrophy","increased pancreatic beta cell number","absent oligodendrocytes","abnormal radial glial cell morphology","decreased heart right ventricle size","abnormal capillary morphology","abnormal long bone epiphyseal plate proliferative zone","increased hemangiosarcoma incidence","oxidative stress","kidney cysts","abnormal hair follicle development","absent platelets","pallor","abnormal pericyte morphology","abnormal neural tube closure","increased tumor growth/size","abnormal long bone morphology","increased autoantibody level","abnormal retinal layer morphology","abnormal retinal inner nuclear layer morphology","abnormal palate morphology","decreased palatal length","abnormal thymus physiology","abnormal imprinting","abnormal bone structure","abnormal compact bone morphology","abnormal Harderian gland pigmentation","abnormal hair shaft morphology","vascular smooth muscle hypoplasia","abnormal eye muscle development","abnormal Mullerian duct morphology","decreased satellite cell number","abnormal coronal suture morphology","skeletal muscle interstitial fibrosis","skeletal muscle necrosis","dry skin","abnormal forelimb zeugopod morphology","lymph node inflammation","abnormal defecation","abnormal feces composition","abnormal myelin sheath morphology","pharyngeal arch hypoplasia","absent pharyngeal arches","abnormal serotonergic neuron morphology","abnormal ear physiology","enlarged stomach","decreased macrophage cell number","increased hepatocyte apoptosis","liver hemorrhage","increased hepatocyte proliferation","prolonged PR interval","increased kidney weight","abnormal heart right ventricle morphology","abnormal heart left ventricle morphology","increased heart rate variability","abnormal pancreas development","abnormal reproductive system development","abnormal gas homeostasis","abnormal circulating lipid level","abnormal hormone level","abnormal nitric oxide homeostasis","increased lean body mass","decreased lean body mass","abnormal noradrenaline level","embryonic growth retardation","renal fibrosis","increased mortality induced by ionizing radiation","abnormal ventral spinal root morphology","decreased thermal nociceptive threshold","abnormal lung vasculature morphology","decreased bone mass","abnormal rod electrophysiology","abnormal cone electrophysiology","abnormal chromosome number","aneuploidy","polyploidy","spontaneous chromosome breakage","aortic dissection","abnormal mitosis","increased acute promyelocytic leukemia incidence","thin myocardium compact layer","caudal body truncation","abnormal vitelline vascular remodeling","abnormal striatum morphology","abnormal sarcomere morphology","abnormal Z line morphology","abnormal spinal cord interneuron morphology","abnormal brain interneuron morphology","abnormal dorsal striatum morphology","lymphatic vessel hyperplasia","abnormal coronary artery morphology","abnormal sinoatrial node morphology","abnormal sarcolemma morphology","abnormal respiratory quotient","abnormal chest morphology","abnormal gastric parietal cell morphology","muscle hypertonia","increased compact bone thickness","retroesophageal right subclavian artery","abnormal adenohypophysis morphology","abnormal lateral geniculate nucleus morphology","abnormal intervertebral disk morphology","transmission ratio distortion","decreased fetal size","fetal growth retardation","increased squamous cell carcinoma incidence","increased basal cell carcinoma incidence","abnormal long bone diaphysis morphology","abnormal myocardial fiber physiology","absent Schlemm's canal","increased cellular sensitivity to ionizing radiation","abnormal embryonic erythropoiesis","small pancreas","abnormal maternal decidual layer morphology","small placenta","abnormal optic stalk morphology","abnormal basement membrane morphology","abnormal embryonic/fetal subventricular zone morphology","abnormal postnatal subventricular zone morphology","abnormal medial ganglionic eminence morphology","abnormal proprioceptive neuron morphology","vestibular ganglion degeneration","absent vestibular saccule","absent femur","bowed tibia","cochlear hair cell degeneration","absent utricle","bowed femur","absent frontal bone","small frontal bone","short frontal bone","absent interparietal bone","abnormal CD8-positive","alpha-beta T cell physiology","abnormal cochlear outer hair cell morphology","small occipital bone","abnormal pterygoid process morphology","absent pterygoid process","absent alisphenoid bone","alisphenoid bone hypoplasia","small nasal bone","short nasal bone","absent nasal bone","abnormal conjunctival epithelium morphology","decreased response of heart to induced stress","increased incidence of tumors by chemical induction","decreased incidence of tumors by chemical induction","decreased renal glomerulus number","abnormal pubis morphology","abnormal ischium morphology","abnormal pelvic girdle bone morphology","abnormal vestibular hair cell stereociliary bundle morphology","short vestibular hair cell stereocilia","abnormal cochlear hair cell stereociliary bundle morphology","decreased cochlear hair cell stereocilia number","abnormal inner hair cell stereociliary bundle morphology","short inner hair cell stereocilia","absent maxilla","abnormal inner hair cell synaptic ribbon morphology","small myocardial fiber","myocardial fiber degeneration","abnormal vertebral arch morphology","vertebral fusion","small vertebrae","caudal vertebral transformation","cervical vertebral transformation","lumbar vertebral transformation","thoracic vertebral transformation","cervical vertebral fusion","decreased lumbar vertebrae number","decreased thoracic vertebrae number","absent caudal vertebrae","small sacral vertebrae","short ribs","thin ribs","rib fractures","decreased length of long bones","decreased circulating insulin-like growth factor I level","abnormal vertebral column morphology","short vertebral body","short lumbar vertebrae","notochord degeneration","truncated notochord","abnormal platelet morphology","abnormal nasal capsule morphology","increased susceptibility to age-related hearing loss","abnormal kidney collecting duct morphology","abnormal loop of Henle morphology","decreased mitotic index","increased mitotic index","increased anti-double stranded DNA antibody level","abnormal axonal transport","abnormal synaptic vesicle recycling","increased anti-single stranded DNA antibody level","abnormal dorsal aorta morphology","increased bile salt level","abnormal synaptic vesicle number","decreased susceptibility to experimental autoimmune encephalomyelitis","absent oocytes","abnormal hematopoietic stem cell morphology","increased hematopoietic stem cell number","decreased hematopoietic stem cell number","abnormal neuron physiology","abnormal somatic hypermutation frequency","abnormal class switch recombination","decreased skeletal muscle mass","long incisors","abnormal small intestine crypts of Lieberkuhn morphology","abnormal large intestine crypts of Lieberkuhn morphology","abnormal Paneth cell morphology","decreased testis weight","decreased ovary weight","dilated kidney collecting duct","lung cysts","abnormal vascular wound healing","increased energy expenditure","decreased energy expenditure","decreased adiponectin level","increased uterus weight","decreased uterus weight","abnormal common crus morphology","decreased epididymis weight","abnormal epididymis epithelium morphology","impaired branching involved in ureteric bud morphogenesis","dilated vasculature","abnormal B cell morphology","abnormal regulatory T cell morphology","abnormal regulatory T cell physiology","skin inflammation","abnormal neuronal precursor proliferation","abnormal brain vasculature morphology","increased spleen weight","decreased spleen weight","decreased thymus weight","enlarged prostate gland","increased prostate gland weight","pale kidney","abnormal regulatory T cell number","increased regulatory T cell number","decreased regulatory T cell number","decreased B-1 B cell number","increased neuronal precursor cell number","decreased neuronal precursor cell number","abnormal osteoclast morphology","increased osteoclast cell number","decreased osteoclast cell number","abnormal osteoblast morphology","increased osteoblast cell number","decreased osteoblast cell number","decreased bone strength","increased bone resorption","decreased bone resorption","abnormal osteoblast physiology","increased eosinophil cell number","decreased eosinophil cell number","increased lymphocyte cell number","increased B cell number","increased T cell number","decreased lymphocyte cell number","decreased B cell number","decreased T cell number","abnormal wound healing","abnormal response to infection","decreased susceptibility to parasitic infection","increased susceptibility to parasitic infection","abnormal trophoblast layer morphology","abnormal ectoplacental cone morphology","abnormal trophoblast giant cell morphology","diarrhea","abnormal MHC II cell surface expression on macrophages","abnormal neutrophil morphology","impaired natural killer cell mediated cytotoxicity","abnormal melanosome morphology","abnormal cell differentiation","decreased acute inflammation","increased acute inflammation","decreased double-negative T cell number","increased double-negative T cell number","increased double-positive T cell number","decreased double-positive T cell number","decreased B cell proliferation","decreased T cell proliferation","abnormal choroid pigmentation","abnormal retinal pigmentation","abnormal ulna morphology","premature hair loss","decreased circulating growth hormone level","decreased cardiac muscle contractility","liver hyperplasia","cachexia","pancytopenia","increased B cell proliferation","bradykinesia","azoospermia","abnormal response to injury","increased susceptibility to injury","decreased susceptibility to injury","abnormal blood-brain barrier function","increased circulating cholesterol level","decreased circulating cholesterol level","head tilt","abnormal anterior eye segment morphology","abnormal uvea morphology","abnormal retinal pigment epithelium morphology","lethargy","abnormal eye anterior chamber morphology","abnormal pancreatic islet morphology","abnormal pancreatic alpha cell morphology","abnormal pancreatic beta cell morphology","abnormal exocrine pancreas morphology","abnormal rostral-caudal axis patterning","increased brain size","abnormal amacrine cell morphology","abnormal retinal ganglion layer morphology","hemopericardium","abnormal eye physiology","abnormal intraocular pressure","ocular hypertension","coloboma","glomerulosclerosis","abnormal brainstem morphology","abnormal fatty acid level","increased fatty acid level","abnormal oxygen consumption","increased oxygen consumption","decreased oxygen consumption","improved glucose tolerance","impaired glucose tolerance","abnormal humerus morphology","spina bifida occulta","head tossing","abnormal salivary gland physiology","pericardial effusion","increased triglyceride level","decreased triglyceride level","abnormal enzyme/coenzyme level","ascites","abnormal renal glomerulus morphology","abnormal podocyte morphology","abnormal myocardium layer morphology","insulin resistance","decreased heart rate","increased circulating aspartate transaminase level","increased T cell proliferation","renal/urinary system phenotype","muscle phenotype","liver/biliary system phenotype","limbs/digits/tail phenotype","adipose tissue phenotype","homeostasis/metabolism phenotype","hearing/vestibular/ear phenotype","growth/size/body region phenotype","endocrine/exocrine gland phenotype","embryo phenotype","digestive/alimentary phenotype","craniofacial phenotype","cellular phenotype","cardiovascular system phenotype","behavior/neurological phenotype","immune system phenotype","respiratory system phenotype","reproductive system phenotype","skeleton phenotype","vision/eye phenotype","taste/olfaction phenotype","hematopoietic system phenotype","abnormal action potential","abnormal nerve conduction","abnormal axon morphology","axon degeneration","abnormal circulating protein level","abnormal circulating hormone level","osteosclerosis","increased macrophage cell number","absent fibula","abnormal food intake","abnormal energy expenditure","decreased percent body fat/body weight","abnormal CD4-positive","alpha-beta T cell physiology","abnormal T-helper 1 physiology","abnormal T-helper 2 physiology","increased circulating thyroxine level","decreased circulating thyroxine level","increased circulating triiodothyronine level","increased chronic myelocytic leukemia incidence","bronchial epithelial hyperplasia","stomach epithelial hyperplasia","abnormal skin physiology","abnormal tendon morphology","thrombocytosis","abnormal skeleton morphology","abnormal body temperature","corneal vascularization","decreased cornea thickness","choroidal neovascularization","abnormal Muller cell morphology","retinal pigment epithelium atrophy","abnormal eye electrophysiology","increased circulating glucose level","decreased circulating glucose level","increased mean corpuscular hemoglobin","decreased mean corpuscular hemoglobin","increased hemoglobin content","increased blood urea nitrogen level","increased pulmonary ventilation","abnormal enzyme/coenzyme activity","increased tidal volume","abnormal vascular smooth muscle morphology","decreased ventricle muscle contractility","increased angiogenesis","decreased angiogenesis","neuron hypertrophy","increased bone mass","increased bleeding time","abnormal cell physiology","decreased dopamine level","abnormal hypothalamus physiology","abnormal limb bud morphology","increased susceptibility to diet-induced obesity","decreased susceptibility to diet-induced obesity","decreased circulating adrenaline level","decreased circulating noradrenaline level","increased circulating noradrenaline level","decreased circulating leptin level","increased circulating leptin level","abnormal white adipose tissue physiology","abnormal corneal epithelium morphology","abnormal intestinal transit time","abnormal basal ganglion morphology","abnormal endolymphatic duct morphology","decreased tympanic ring size","impaired lung alveolus development","abnormal mitochondrion morphology","abnormal mitochondrial physiology","increased mitochondrial fission","increased apoptosis","decreased apoptosis","pulmonary fibrosis","spinal hemorrhage","abnormal vascular endothelial cell morphology","increased vascular endothelial cell number","decreased cerebral infarction size","abnormal retinal neuronal layer morphology","CNS inflammation","abnormal vestibular saccule morphology","arteriovenous malformation","absent amacrine cells","abnormal tectum morphology","abnormal heart septum morphology","abnormal cardiac outflow tract development","congestive heart failure","decreased visual acuity","embryonic lethality during organogenesis","lethality throughout fetal growth and development","impaired pupillary reflex","abnormal involution of the mammary gland","abnormal limb development","abnormal tail development","abnormal spinal cord dorsal horn morphology","increased medulloblastoma incidence","abnormal nasal placode morphology","abnormal platelet activation","abnormal mesenchyme morphology","abnormal retinal nerve fiber layer morphology","decreased retinal ganglion cell number","increased myocardial fiber number","abnormal perichondrium morphology","impaired hearing","abnormal susceptibility to hearing loss","small pharyngeal arch","absent startle reflex","abnormal male germ cell morphology","abnormal spermatid morphology","decreased long bone epiphyseal plate size","disorganized long bone epiphyseal plate","dorsal root ganglion hypoplasia","abnormal common myeloid progenitor cell morphology","increased T cell apoptosis","decreased T cell apoptosis","increased ovary tumor incidence","early cellular replicative senescence","intestine polyps","increased lung tumor incidence","increased liver tumor incidence","increased blastoma incidence","brain vacuoles","abnormal brain white matter morphology","abnormal paraxial mesoderm morphology","decreased Cajal-Retzius cell number","abnormal T cell morphology","increased NK T cell number","decreased NK T cell number","abnormal NK T cell physiology","decreased NK cell number","abnormal memory T cell physiology","abnormal NK cell differentiation","abnormal retinal ganglion cell morphology","abnormal DNA repair","abnormal podocyte foot process morphology","abnormal podocyte slit diaphragm 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number","small Peyer's patches","podocyte foot process effacement","decreased small intestinal villus size","abnormal dendrite morphology","asymmetric sternocostal joints","decreased diameter of femur","decreased diameter of tibia","increased diameter of femur","increased diameter of tibia","abnormal B-2 B cell morphology","increased B-1a cell number","decreased B-1a cell number","abnormal follicular B cell morphology","increased follicular B cell number","decreased follicular B cell number","increased germinal center B cell number","decreased germinal center B cell number","absent germinal center B cells","increased marginal zone B cell number","decreased marginal zone B cell number","absent marginal zone B cells","decreased naive B cell number","increased pro-B cell number","decreased transitional stage B cell number","abnormal germinal center B cell physiology","abnormal marginal zone B cell physiology","decreased B-2 B cell number","decreased pro-B cell number","decreased pre-B cell number","increased mature B cell number","decreased mature B cell number","absent mature B cells","absent immature B cells","decreased immature B cell number","abnormal B cell activation","increased susceptibility to neuronal excitotoxicity","decreased susceptibility to neuronal excitotoxicity","abnormal leukocyte morphology","abnormal common lymphocyte progenitor cell morphology","abnormal myeloid leukocyte morphology","increased megakaryocyte cell number","decreased megakaryocyte cell number","abnormal myometrium morphology","abnormal autophagy","arrest of male meiosis","abnormal bone ossification","abnormal intramembranous bone ossification","failure of endochondral bone ossification","abnormal male germ cell apoptosis","adrenal medulla hyperplasia","small adenohypophysis","decreased somatotroph cell number","decreased gonadotroph cell number","decreased corticotroph cell number","increased gamma-delta T cell number","decreased gamma-delta T cell number","absent gamma-delta T cells","small malleus","small malleus manubrium","hypochromic microcytic anemia","decreased primordial germ cell number","abnormal osteoblast differentiation","abnormal osteoclast differentiation","abnormal spatial reference memory","abnormal long term spatial reference memory","abnormal cutaneous collagen fibril morphology","abnormal cortical plate morphology","abnormal retinal cone cell outer segment morphology","retinal photoreceptor degeneration","abnormal cortical intermediate zone morphology","abnormal medium spiny neuron morphology","abnormal spleen B cell follicle morphology","absent spleen germinal center","intermingled spleen red and white pulp","increased spleen red pulp amount","decreased spleen red pulp amount","increased spleen white pulp amount","decreased spleen white pulp amount","increased spleen germinal center number","decreased spleen germinal center number","increased spleen germinal center size","decreased spleen germinal center size","slow postnatal weight gain","decreased IgG1 level","decreased IgG2a level","decreased IgG2b level","decreased IgG3 level","increased IgG1 level","increased IgG2a level","increased IgG2b level","increased IgG3 level","thin retinal ganglion layer","thin retinal inner nuclear layer","absent retinal inner plexiform layer","thin retinal outer nuclear layer","retinal outer nuclear layer degeneration","polycystic kidney","decreased chemical nociceptive threshold","enlarged lateral ventricles","decreased susceptibility to induced colitis","abnormal vesicle-mediated transport","abnormal neocortex morphology","increased circulating tumor necrosis factor level","abnormal interferon-gamma secretion","increased tumor necrosis factor secretion","decreased tumor necrosis factor secretion","increased interferon-gamma secretion","decreased interferon-gamma secretion","increased circulating interferon-gamma level","decreased circulating interferon-gamma level","disorganized photoreceptor outer segment","abnormal circulating interleukin level","increased circulating interleukin-10 level","increased circulating interleukin-6 level","decreased circulating interleukin-6 level","increased circulating interleukin-2 level","increased circulating interleukin-4 level","decreased circulating interleukin-4 level","increased circulating interleukin-17 level","increased circulating interleukin-18 level","increased circulating interleukin-1 alpha level","increased circulating interleukin-1 beta level","increased circulating interleukin-12b level","decreased interleukin-1 beta secretion","increased interleukin-10 secretion","increased interleukin-13 secretion","decreased interleukin-13 secretion","increased interleukin-17 secretion","increased interleukin-2 secretion","decreased interleukin-2 secretion","increased interleukin-4 secretion","increased interleukin-5 secretion","decreased interleukin-5 secretion","increased interleukin-6 secretion","abnormal cytokine level","increased lung carcinoma incidence","increased 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amount","abnormal suprachiasmatic nucleus morphology","retinal neovascularization","abnormal hair cycle anagen phase","abnormal hair cycle catagen phase","abnormal hair cycle telogen phase","chromosomal instability","abnormal granulosa cell morphology","abnormal physiological response to xenobiotic","decreased physiological sensitivity to xenobiotic","abnormal DNA methylation","abnormal enterocyte proliferation","abnormal enterocyte apoptosis","increased enterocyte apoptosis","decreased hepatocyte apoptosis","absent epididymal fat pad","fused carpal bones","abnormal astrocyte physiology","abnormal oligodendrocyte physiology","decreased mean platelet volume","reticulocytopenia","decreased sensitivity to induced cell death","increased neuron number","decreased neuron number","increased carbon dioxide production","decreased erythroid progenitor cell number","delayed female fertility","progressive hair loss","prolonged diestrus","prolonged estrus","abnormal spinal cord meninges morphology","abnormal hallux morphology","dilated proximal convoluted tubules","anal stenosis","endometrium hyperplasia","oocyte degeneration","penis prolapse","increased pancreas weight","decreased pancreas weight","decreased pancreatic beta cell mass","decreased white fat cell number","abnormal white fat cell size","increased prepulse inhibition","abnormal pancreatic duct morphology","increased pancreatic ductal adenocarcinoma incidence","increased pancreatic intraepithelial neoplasia incidence","increased pancreas tumor incidence","absent pancreatic acini","increased pancreatic acinar cell number","abnormal pancreatic acinar cell zymogen granule morphology","exocrine pancreas atrophy","abnormal endocrine pancreas morphology","increased pancreatic islet number","decreased pancreatic islet number","small pancreatic islets","absent pancreatic islets","abnormal pancreatic beta cell differentiation","increased pancreatic alpha cell number","decreased pancreatic alpha cell number","absent pancreatic alpha cells","abnormal pancreatic alpha cell differentiation","increased pancreatic delta cell number","increased prostate intraepithelial neoplasia incidence","increased prostate gland adenocarcinoma incidence","hairpin sperm flagellum","pale spleen","failure of eyelid fusion","abnormal cerebellum fissure morphology","decreased fat cell size","decreased guard hair length","buphthalmos","increased brain tumor incidence","abnormal bone marrow cell physiology","decreased gonadal fat pad weight","increased abdominal fat pad weight","decreased epididymal fat pad weight","decreased inguinal fat pad weight","increased retroperitoneal fat pad weight","increased small intestine adenocarcinoma incidence","increased follicular lymphoma incidence","increased histiocytic sarcoma incidence","decreased splenocyte number","decreased trabecular bone thickness","increased trabecular bone thickness","impaired spacing of implantation sites","twin decidual capsule","increased liver triglyceride level","decreased liver triglyceride level","abnormal endoplasmic reticulum morphology","abnormal prostate gland ventral lobe morphology","abnormal dermal pigmentation","abnormal epidermal pigmentation","abnormal extracutaneous pigmentation","abnormal otic pigmentation","abnormal leptomeninges pigmentation","increased nucleated erythrocyte cell number","increased trophoblast giant cell number","increased skeletal muscle fiber size","decreased skeletal muscle fiber size","decreased skeletal muscle fiber diameter","increased variability of skeletal muscle fiber size","centrally nucleated skeletal muscle fibers","abnormal skeletal muscle fiber type ratio","skeletal muscle fiber degeneration","skeletal muscle fiber atrophy","skeletal muscle fiber necrosis","skeletal muscle fibrosis","skeletal muscle endomysial fibrosis","paraparesis","abnormal axon fasciculation","abnormal synaptonemal complex","enhanced contextual conditioning behavior","skeletal muscle hypertrophy","abnormal cecum development","abnormal intrahepatic bile duct morphology","abnormal mammary gland duct morphology","abnormal mammary gland alveolus morphology","distended stomach","enlarged salivary gland","increased thymocyte apoptosis","decreased thymocyte apoptosis","abnormal thymus corticomedullary boundary morphology","abnormal thymus epithelium morphology","absent gastric milk in neonates","decreased platelet aggregation","increased urinary bladder carcinoma incidence","urinary bladder obstruction","mitotic nondisjunction","abnormal right lung accessory lobe morphology","abnormal right lung cranial lobe morphology","abnormal right lung middle lobe morphology","abnormal developmental vascular remodeling","acephaly","increased keratinocyte proliferation","enlarged inguinal lymph nodes","enlarged popliteal lymph nodes","abnormal eyelid development","abnormal secondary palate development","failure of chorioallantoic fusion","abnormal induced retinal neovascularization","abnormal uterine-embryonic axis","abnormal embryo attachment","abnormal uterus physiology","decreased birth body size","increased skin squamous cell carcinoma incidence","enhanced conditioned place preference behavior","abnormal calcaneum morphology","enlarged prostate gland anterior lobe","preaxial polydactyly","postaxial polydactyly","impaired behavioral response to cocaine","abnormal mitotic spindle morphology","abnormal mitotic spindle assembly checkpoint","increased sensitivity to induced morbidity/mortality","decreased sensitivity to induced morbidity/mortality","increased sensitivity to xenobiotic induced morbidity/mortality","impaired somite development","abnormal chondrocyte physiology","abnormal melanoblast morphology","abnormal melanoblast migration","altered susceptibility to infection induced morbidity/mortality","increased susceptibility to bacterial infection induced morbidity/mortality","abnormal mismatch repair","decreased oligodendrocyte number","cornea ulcer","increased tumor latency","impaired gastric peristalsis","abnormal aorta elastic tissue morphology","abnormal ascending aorta morphology","abnormal aorta tunica adventitia morphology","failure of palatal shelf elevation","abnormal frontonasal prominence morphology","decreased tongue size","abnormal transitional stage T3 B cell morphology","increased transitional stage T1 B cell number","decreased transitional stage T1 B cell number","decreased transitional stage T2 B cell number","skin fibrosis","abnormal tail hair pigmentation","abnormal hind foot hair pigmentation","abnormal dendritic spine morphology","abnormal neuron differentiation","abnormal cerebellum vermis lobule morphology","abnormal cerebellum hemisphere lobule morphology","abnormal cerebellum lobule morphology","abnormal cerebellar granule cell precursor proliferation","abnormal cerebral cortex pyramidal cell morphology","cerebral cortex pyramidal cell degeneration","abnormal cuticular plate morphology","pulmonary vascular congestion","liver vascular congestion","increased total body fat amount","decreased total body fat amount","abnormal cranium size","ectopic melanocytes","abnormal placenta physiology","abnormal trophoblast giant cell proliferation","hypermyelination","decreased grip strength","increased serotonin level","increased pruritus","decreased pruritus","abnormal hepatocyte physiology","abnormal retinal blood vessel morphology","abnormal retinal blood vessel pattern","abnormal thoracic cage shape","small thoracic cage","decreased bone mineral content","decreased DN2 thymocyte number","abnormal tumor vascularization","abnormal intestine physiology","abnormal small intestinal crypt cell physiology","abnormal small intestinal crypt cell proliferation","abnormal intestine development","increased oligodendrocyte number","abnormal centroacinar cell of Langerhans morphology","abnormal mammary gland epithelium physiology","decreased mammary gland epithelial cell proliferation","increased susceptibility to weight loss","enlarged lymphatic vessel","abnormal telomere morphology","abnormal circulating chemokine level","abnormal circulating cytokine level","increased T-helper 17 cell number","abnormal T-helper 17 cell differentiation","abnormal heart ventricle outflow tract morphology","abnormal retina inner limiting membrane morphology","abnormal retina outer limiting membrane morphology","decreased lymphoma incidence","decreased mammary gland tumor incidence","increased classified tumor incidence","increased organ/body region tumor incidence","increased melanoma incidence","increased intraocular melanoma incidence","increased astrocytoma incidence","increased glioma incidence","increased gastrointestinal tumor incidence","increased nervous system tumor incidence","increased plasmacytoma incidence","increased kidney tumor incidence","increased hemolymphoid system tumor incidence","increased mammary gland tumor incidence","increased skin tumor incidence","abnormal tumor latency","decreased tumor latency","increased oligodendroglioma incidence","increased cholangiocarcinoma incidence","increased pituitary gland tumor incidence","increased acute lymphoblastic leukemia incidence","increased prostate gland tumor incidence","increased liver free fatty acids level","increased fibrosarcoma incidence","increased thymus tumor incidence","myeloid hyperplasia","abnormal gut flora balance","increased respiratory quotient","abnormal dosage compensation","by inactivation of X chromosome","increased adenoma incidence","abnormal Bergmann glial cell morphology","abnormal pharyngeal arch development","decreased liver glycogen level","increased skeletal muscle glycogen level","ventricular septal defect","vascular ring","abnormal heart electrocardiography waveform feature","atrioventricular block","calcified aorta","gastrointestinal arteriovenous malformation","tumor regression","abnormal conotruncus septation","abnormal cardiac muscle tissue morphology","cardiac muscle necrosis","myocardial hypertrophy","increased QRS amplitude","altered tumor pathology","thick myocardium","absent sclera","thin interventricular septum","increased glioblastoma incidence","abnormal melanocyte proliferation","abnormal heart left ventricle pressure","abnormal hematopoietic stem cell physiology","abnormal NK cell physiology","mortality/aging","abnormal survival","integument phenotype","abnormal forestomach morphology","abnormal stomach mucosa morphology","abnormal intermediate gastric gland morphology","abnormal intestinal enteroendocrine cell morphology","abnormal Clara cell morphology","decreased type II pneumocyte number","abnormal bronchioalveolar stem cell morphology","lethality","incomplete penetrance","increased effector memory CD8-positive","alpha-beta T cell number","abnormal bone trabecula morphology","increased bone trabecula number","decreased bone trabecula number","increased trabecular bone mass","decreased trabecular bone mass","increased bone 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atrophy","expanded mesangial matrix","decreased kidney apoptosis","renal glomerulus fibrosis","absent metanephric mesenchyme","absent heart","increased fetal cardiomyocyte proliferation","lethality","complete penetrance","increased renal glomerulus basement membrane thickness","mesangial cell hyperplasia","mesangiolysis","increased kidney cell proliferation","decreased dopaminergic neuron number","decreased susceptibility to dopaminergic neuron neurotoxicity","abnormal metanephric ureteric bud development","abnormal head size","abnormal glomerular capsule parietal layer morphology","decreased placental labyrinth size","decreased alkaline phosphatase activity","increased mitochondria number","decreased mitochondria number","increased mitochondria size","dilated mitochondria","abnormal mitochondrial shape","abnormal mitochondrial inner membrane morphology","abnormal mitochondrial crista morphology","abnormal bone collagen fibril morphology","abnormal tendon collagen fibril morphology","abnormal olfactory sensory neuron physiology","renal glomerulus cysts","decreased fibroblast proliferation","absent fibroblast proliferation","abnormal fibroblast migration","decreased fibroblast cell migration","ectopic neuron","increased myelin sheath thickness","decreased myelin sheath thickness","decreased somite size","abnormal Golgi apparatus morphology","myelofibrosis","intestinal fibrosis","abnormal genital tubercle morphology","rectal atresia","rectourethral fistula","decreased pancreatic beta cell proliferation","abnormal hematopoietic stem cell proliferation","increased hematopoietic stem cell proliferation","abnormal circulating osteocalcin level","abnormal endocrine pancreas development","increased food intake","decreased food intake","decreased fluid intake","decreased cardiac stroke volume","abnormal eye anterior chamber depth","increased or absent threshold for auditory brainstem response","increased nerve conduction velocity","abnormal melanocyte number","decreased melanocyte number","increased susceptilbility to retinal ischemic injury","decreased susceptilbility to retinal ischemic injury","increased astrocyte number","decreased astrocyte number","impaired mammary gland growth during pregnancy","delayed heart development","absent midbrain","decreased midbrain size","absent spongiotrophoblast","absent midbrain-hindbrain boundary","decreased forebrain size","absent hindbrain","flat head","abnormal head development","abnormal splanchnic mesoderm morphology","decreased paraxial mesoderm size","increased endothelial cell proliferation","decreased endothelial cell proliferation","abnormal neuronal stem cell physiology","increased neuronal stem cell self-renewal","decreased neuronal stem cell self-renewal","enhanced spatial learning","increased large unstained cell number","decreased alimentary system tumor incidence","increased lymphoma incidence","abnormal cochlear VIII nucleus morphology","increased cell death","increased noradrenaline level","tomacula","delayed caudal neuropore closure","abnormal behavioral response to methamphetamine","abnormal cardiac neural crest cell morphology","increased cardiac neural crest cell number","decreased cardiac neural crest cell number","impaired cardiac neural crest cell differentiation","abnormal cardiac neural crest cell migration","impaired cranial neural crest cell differentiation","decreased rhombomere 1 size","abnormal enteric neural crest cell migration","thin body","moribund","truncated tail bud","hemorrhagic ascites","abnormal primary cilium morphology","pancreatic acinar-to-ductal metaplasia","abnormal third pharyngeal pouch morphology","abnormal skeletal muscle regeneration","impaired skeletal muscle regeneration","abnormal extracellular matrix morphology","decreased fasted circulating glucose level","abnormal mitotic cytokinesis","embryonic lethality prior to tooth bud stage","osteophytes","increased adrenal gland weight","visceromegaly","hepatic peliosis","increased sebaceous gland tumor incidence","abnormal CD8-positive","naive alpha-beta T cell number","decreased conjunctiva goblet cell number","abnormal conjunctiva goblet cell differentiation","abnormal ileum crypts of Lieberkuhn morphology","abnormal duodenum crypts of Lieberkuhn morphology","abnormal jejunum crypts of Lieberkuhn morphology","increased Paneth cell number","increased keratoacanthoma incidence","increased embryonic tissue cell apoptosis","testis degeneration","increased femur compact bone thickness","increased bone trabecular spacing","decreased bone trabecular spacing","decreased bone stiffness","increased myeloid cell number","increased granulocyte monocyte progenitor cell number","abnormal mature B cell number","abnormal conjunctival sac morphology","abnormal colon goblet cell morphology","myeloid metaplasia","preputial gland inflammation","abnormal plasmablast number","decreased small intestine length","increased T cell acute lymphoblastic leukemia incidence","increased male germ cell apoptosis","nervous system inclusion bodies","increased cardiac muscle glycogen level","absent Paneth cells","ectopic Paneth cells","small intestinal villus atrophy","fused small intestinal villi","decreased small intestinal villus height","blunted small intestinal villi","decreased chondrocyte proliferation","delayed chondrocyte differentiation","increased mammary gland apoptosis","increased thymoma incidence","abnormal embryo morphology","abnormal mesoderm morphology","decreased body fat mass","decreased fatty acid oxidation","decreased fatty acid beta-oxidation","abnormal blood-retinal barrier function","cerebellum atrophy","epididymis hypertrophy","spermatocele","epididymis fibrosis","increased epididymal cell proliferation","increased epididymal epithelium cell proliferation","increased bone ossification","decreased bone ossification","increased neocortex size","increased bone mineralization","decreased bone mineralization","delayed bone mineralization","altered susceptibility to bacterial infection","decreased collagen level","abnormal capillary branching pattern","decreased capillary density","increased endoplasmic reticulum stress","increased heart iron level","increased intestinal iron level","decreased kidney epithelial cell primary cilium length","abnormal cardiac thrombosis","increased liposarcoma incidence","increased abdominal adipose tissue amount","decreased fibroblast chemotaxis","decreased platelet alpha-granule number","abnormal circardian behavior entrainment","decreased dendritic spine density","browned white adipose tissue morphology","decreased susceptibility to induced hypothermia","giant platelets","short face","broad face","macrodontia","round head","small mandibular condyloid process","thick neurocranium","thin neurocranium","small mandibular coronoid process","enlarged occipital bone","abnormal face development","premature coronal suture closure","premature metopic suture closure","enlarged 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"code_internal":"C57BL/6N-Stat1, Gt(ROSA)26Sor, Col1a1", "_version_":1837343092258111488 }] } }