Service Description:

The Centre for Phenogenomics (TCP) produces and phenotypes mouse models for discovery and biomedical research. TCP’s team of experts and state-of-the-art infrastructure are available to help scientists advance their research programs by developing and phenotyping mouse models of development and disease. Leverage our expertise for all aspects of your mouse research so you can focus on data interpretation and research outcomes.

Clinical Phenotyping: In vivo mouse phenotyping across a range of body systems for research, preclinical assessment and/or drug target validation and treatment effect.

Included in the Service:

TCP works with clients to develop project plans that best suit their needs. Costs are based on the project plan. We can provide cost estimates, statements of work, and/or letters of support for budgetary purposes and grant applications.

Additional Services & Support:

Animal Resources: Ethics review and approval, animal husbandry, and veterinary and technical services for in vivo research projects.

Imaging: Multi-modal imaging technologies for three-dimensional analysis of mouse anatomical phenotypes and more.

Pathology: Tissue analyses using histology with routine and special stains, immunohistochemistry, and immunofluorescence, along with a full range of digital pathology and image analysis.

Archiving & Distribution: Mouse line cryopreservation and reanimation as well as global acquisition and distribution of mouse lines.

Model Production: Design, produce and quality control genetically engineered mouse lines.

TCP collaborates with multiple research service providers to ensure our clients have access to cutting-edge technologies across domains for their research projects:

• Infection studies with bacteria, viruses, parasites, and fungi in CL2 and CL3 as well as inflammatory models are supported by our collaborators at the McGill Infection and Inflammation Platform.
• Proteomics and metabolomics studies, including several quantitative mouse tissue proteomics assays developed in collaboration with TCP, can be executed at the Proteomics Centre at the University of Victoria.
• Sanger and next generation sequencing for quality control of animal models and transcriptomics are conducted at The Centre for Applied Genomics.