IMPC phenotypes (gene matching)
B6.129S2-Trmt1lGt(W027A02)Wrst/Ieg
| Status | Available to order |
| EMMA ID | EM:05697 |
| International strain name | B6.129S2-Trmt1lGt(W027A02)Wrst/Ieg |
| Alternative name | Trmt1l (TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)) |
| Strain type | Gene-trap |
| Allele/Transgene symbol | Trmt1lGt(W027A02)Wrst |
| Gene/Transgene symbol | Trmt1l |
Information from provider
| Provider | Franz Vauti |
| Provider affiliation | Cell- & Molecular Biology, Technical University of Braunschweig |
| Genetic information | Trmt1l PT1betageo gene-trap. |
| Phenotypic information | Neurobiological phenotype. |
| Breeding history | Backcrossed to C57BL/6 (N>5). |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
Literature references
- A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.;Hansen Jens, Floss Thomas, Van Sloun Petra, Füchtbauer Ernst-Martin, Vauti Franz, Arnold Hans-Hennig, Schnütgen Frank, Wurst Wolfgang, von Melchner Harald, Ruiz Patricia, ;2003;Proceedings of the National Academy of Sciences of the United States of America;100;9918-22; 12904583
- Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells.;Wiles M V, Vauti F, Otte J, Füchtbauer E M, Ruiz P, Füchtbauer A, Arnold H H, Lehrach H, Metz T, von Melchner H, Wurst W, ;2000;Nature genetics;24;13-4; 10615117
- The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour.;Vauti Franz, Goller Tobias, Beine Rafael, Becker Lore, Klopstock Thomas, Hölter Sabine M, Wurst Wolfgang, Fuchs Helmut, Gailus-Durner Valerie, de Angelis Martin Hrabé, Arnold Hans-Henning, ;2007;Gene;389;174-85; 17198746