INFRAFRONTIER-I3 / Mouse Metabolic Phenotyping Training Course

August 10, 2016

October 10th – October 13th at the German Mouse Clinic, Helmholtz Centre Munich

INFRAFRONTIER, the European Research Infrastructure for phenotyping and archiving of model mammalian genomes, offers an excellent training opportunity in mouse metabolic phenotyping. The course will be run by the German Mouse Clinic (GMC) based at the Helmholtz Centre Munich (https://www.mouseclinic.de/index.html), and will cover state of the art phenotyping assays used in the energy metabolism, diabetes, clinical chemistry and pathology screens of the GMC. All assays are routinely applied in systemic phenotyping projects of the GMC, and in part also in the phenotyping pipeline of the International Mouse Phenotyping Consortium (IMPC). The course will be run by highly experienced scientists of the GMC, and involve presentations and extensive discussions of assays, experimental design and data analyses.

Course content

Day 1 / October 10th / starting at 12.00

German Mouse Clinic phenotyping pipelines, INFRAFRONTIER
Glucose metabolism, glucose tolerance test
Clamp technologies

Day 2 / October 11th

Metabolic phenotyping
Clinical chemistry / liver enzymes
Pathology and histological analyses
Tour of German Mouse Clinic

Day 3 / October 12th

Phenotyping pipeline design
Data analysis, statistics
Liver spectroscopy, Maldi mass spectrometry
Breath gas analysis
Metabolomics
Tour of Helmholtz Genome Analysis Centre (GAC)

Day 4 / October 13th / ending at 17.00

Pigs as animal models for metabolic research
Indirect calorimetry
Human respirometry

Learning objectives

The 4-day course is intending to give participants a comprehensive overview of state of the art technologies and approaches in mouse metabolic phenotyping
A strong focus will be on experimental design and phenotyping data analyses

Prospective attendees

Course level will be at MS, PhD and Postdoc level. No prior experience with metabolic phenotyping required

Information

The training course is limited to a total of 10 participants
Cost: 500€ covering course materials, accommodation, coffee breaks, lunch and course dinner (but excluding travel cost)
Accommodation for course participants has been arranged in the Kurfürst Hotel close to the meeting venue, http://www.kurfuerst-hotel.de/
Registration deadline: September 16th, 2016
Registration: A registration form can be downloaded from the INFRAFRONTIER portal at https://www.infrafrontier.eu/resources-and-services/training-and-consulting-services/phenotyping-training-courses
Contact for further enquiries and submission of applications: genvavat@vasensebagvre.rh