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The INFRAPLUS’s kick-off took place over two productive days in Munich. With lively discussions and concrete plans, we have set the stage for INFRAFRONTIER’s expansion in state-of-the-art in vivo models, innovative in vitro models, preclinical services, and data analysis. All set to get started!
Our partners at NKI and colleagues have developed the OBSERVE guidelines to improve the preparation and reporting of in vivo cancer studies in rodents. The guidelines provide detailed instructions on optimal preparation, implantation methods, and monitoring criteria. They also address expected adverse effects and offer tools to minimise distress and pain in animal models, promoting ethical practices and animal welfare in cancer research.
Under the canSERV Open Call, researchers are invited to apply for a portfolio of services covering the entire oncology developmental pipeline, with the participation of 9 INFRAFRONTIER partners providing in vivo services. Deadline: 4 January 2023
A new publication of INFRAFRONTIER in Mammalian Genome is available on line now. Get an overview of the latest INFRAFRONTIER advancements, including services, resources, and technical developments.
Famous mouse model workshop in Leiden has opened its online registration. The Innovative Mouse Models workshop IMM2021 in Leiden has a long history and is highly acknowledged among biomedical and genetic scientists worldwide. Due to the pandemic situation in Europe, the famous mutant mouse workshop, traditionally held at the Leiden University Medical Center (LUMC) and co-organized by INFRAFRONTIER´s Dutch partner institute NKI, will be presented as a virtual meeting this year for the first time.
GEMM-ESC protocol published in EMBO Molecular Medicine last year, the Netherlands Cancer Institute (NKI) presented a strategy for rapid analysis of gene function in mouse models by deriving and modifying embryonic stem cells (ESC) from validated genetically engineered mouse models (GEMM), the so-called GEMM-ESC strategy.
