STOCK Il10tm1a(EUCOMM)Wtsi/Cnbc
Status | Available to order |
EMMA ID | EM:08502 |
International strain name | STOCK Il10tm1a(EUCOMM)Wtsi/Cnbc |
Alternative name | STOCK.Il10 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Il10tm1a(EUCOMM)Wtsi, |
Gene/Transgene symbol | Il10 |
Information from provider
Provider | Aurora Pujol |
Provider affiliation | Neurosciences. Neurometabolic Diseases, IDIBELL |
Genetic information | Heterozygous mice, carrying a genetically modified tm1a allele of the Il10 gene (produced by EUCOMM; ES cell clone EPD0158_4_D06), were produced at CNB-CSIC, under Infrafrontier-I3 project (WP8 work-package). GLT chimera bred to albino outbred mice. Resulting animals further bred to CD1 for archiving purposes, resulting in a STOCK (albino outbred) genetic background. |
Phenotypic information | Homozygous:None, unless the gene is deleted via cre-loxP strategies.Heterozygous:none |
Breeding history | ES cells from C57BL/6N genetic background resulting in a GLT chimera bred to albino outbred animals. Resulting animals bred to CD1 albino outbred mice for archiving purposes. Mixed background. |
References | None available |
Homozygous fertile | yes |
Homozygous viable | yes |
Homozygous matings required | no |
Immunocompromised | not known |
Information from EMMA
Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
Animals used for archiving | heterozygous mixed |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome / Orphanet_238569
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