Available to order

International strain nameB6;129P2-Grm1tm1Dgen/H
Alternative nameDELTAGEN_T801
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolGrm1tm1Dgen,
Gene/Transgene symbolGrm1

Information from provider

Provider Deltagen Inc.
Provider affiliationDeltagen Inc.
Phenotypic informationHome cage observations: ataxia/lack of coordination, stumbling, paddling movements, hypoactivity, thin, and/or hunched posture, 20 and 49 day cohorts. Physical examination: ataxia, incoordination, runted, thinness and weakness in homozygous mutant mice, 49 day cohort. Necropsy examination: decreased body weights and body lengths in homozygous mutant mice at 49 days. Mouse metrics: decreased body weight, body length, and body weight/body length ratio in a homozygous mutant mouse, 49 day cohort. Juvenile lethality: homozygous mutant mice do not survive to 90 day cohort. There were no significant differences detected in the heterozygous mutant mice when compared with age- and gender-matched wild-type control mice.
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

    • Autosomal recessive congenital cerebellar ataxia due to MGLUR1 deficiency / Orphanet_324262
MGI phenotypes (allele matching)
  • decreased bone mineral density / MGI
  • weakness / MGI
  • decreased body weight / MGI
  • decreased body size / MGI
  • ataxia / MGI
  • hypoactivity / MGI
  • hunched posture / MGI
  • impaired limb coordination / MGI
  • premature death / MGI
  • decreased bone mineral content / MGI

Information on how we integrate external resources can be found here



Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

Not found what you were looking for? Search here for other strains available from EMMA.

INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).