Available to order

International strain nameB6;129S5-Trib2tm1Lex/Orl
Alternative nameLEXKO-1136
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolTrib2tm1Lex,
Gene/Transgene symbolTrib2

Information from provider

Provider Lexicon Genetics, Inc.
Provider affiliationLexicon Pharmaceuticals
Phenotypic informationThe homozygous mutant mice exhibited an increased mean percentage of CD8 cells and a decreased mean percentage of B cells in the peripheral blood when compared with their wild-type littermates and the historical means. The mutants also exhibited decreased exploratory activity during open field activity testing.
Breeding historyIt seems the homozygous females are not very fertile and the best procedure is to cross homozygous males with heterozygous females.
ReferencesNone available

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France

Disease and phenotype information

MGI phenotypes (allele matching)
  • decreased exploration in new environment / MGI
  • decreased B cell number / MGI
  • increased CD8-positive, alpha-beta T cell number / MGI

Information on how we integrate external resources can be found here



Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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