MGI phenotypes (allele matching)
B6;129P2-Prmt2tm1Yah Cstbtm1Yah/+ +/Orl
| Status | Available to order |
| EMMA ID | EM:01810 |
| International strain name | B6;129P2-Prmt2tm1Yah Cstbtm1Yah/+ +/Orl |
| Alternative name | Cis (Hrmt1l1tm1Yah-Cstbtm1Yah) |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Cstbtm1Yah, |
| Gene/Transgene symbol | Cstb |
Information from provider
| Provider | Yann HERAULT |
| Provider affiliation | TAAM-CDTA UPS44, Institut de Transgenose, INTRAGENE |
| Genetic information | Insertion by homologous recombination in ES cells using MICER of a targeting vector containing a loxP site at the Hrmt1l1 (Prmt2) locus and of a second vector, on the same homologous chromosome, containing a loxP site at the Cstb locus (cis configuration of the loxP sites on MMU10). |
| Phenotypic information | No visible phenotype. |
| Breeding history | Targeted mutation generated in 129P2 ES cells. Cells injected in C57BL/6 blastocysts. Backcrossed to C57BL/6, then intercrossed. |
| References |
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Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Unverricht-Lundborg disease / Orphanet_308
- Autosomal recessive hypohidrotic ectodermal dysplasia / Orphanet_248
Literature references
- Inducing segmental aneuploid mosaicism in the mouse through targeted asymmetric sister chromatid event of recombination.;Duchon Arnaud, Besson Vanessa, Pereira Patricia Lopes, Magnol Laetitia, Hérault Yann, ;2008;Genetics;180;51-9; 18757940