Tg(Ins1-CreERT2)16.7.Ics

Status

Available to order

EMMA IDEM:14954
International strain nameTg(Ins1-CreERT2)16.7.Ics
Alternative nameTg(Ins1-CreERT2)16.7.Ics
Strain typeTransgenic Strains
Allele/Transgene symbolTg(Ins1-CreERT2)16.7.Ics
Gene/Transgene symbol

Information from provider

Provider ICS, Institut Clinique de la Souris
Provider affiliationICS, Institut Clinique de la Souris
Genetic informationThe line was obtained by microinjection of a plasmid transgene containing 8.1 kb of the mouse Ins1 promoter region followed by a rabbit-b-globin intron-CreERT2 cassette and a SV40 polyA sequence. The genetic background of the fertilized oocytes was C57BL/6J - SJL/J. The founder was then maintained in a C57BL/6J genetic background. The subline 16.7 was analyzed and cryopreserved. Four copies of transgene are inserted on mouse Chr12.The information available on the characterization of the line, e.g. expression analysis, histology, paper reference, is available on the web page linked here.
Phenotypic informationHomozygous:
NA

Heterozygous:
NA
Breeding historyBackcrossed to C57BL/6N for 9 generations
References
  • Rfx6 maintains the functional identity of adult pancreatic β cells.;Piccand Julie, Strasser Perrine, Hodson David J, Meunier Aline, Ye Tao, Keime Céline, Birling Marie-Christine, Rutter Guy A, Gradwohl Gérard, ;2014;Cell reports;9;2219-32; 25497096
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Literature references

  • Rfx6 maintains the functional identity of adult pancreatic β cells.;Piccand Julie, Strasser Perrine, Hodson David J, Meunier Aline, Ye Tao, Keime Céline, Birling Marie-Christine, Rutter Guy A, Gradwohl Gérard, ;2014;Cell reports;9;2219-32; 25497096

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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