STOCK Slc7a11tm1c(EUCOMM)Wtsi/IcsOrl

Status

Available to order

EMMA IDEM:13218
International strain nameSTOCK Slc7a11tm1c(EUCOMM)Wtsi/IcsOrl
Alternative nameSTOCK Slc7a11 tm1c(EUCOMM)Wtsi/IcsOrl
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolSlc7a11tm1c(EUCOMM)Wtsi
Gene/Transgene symbolSlc7a11

Information from provider

ProviderCécile FREMOND
Provider affiliationCNRS-TAAM
Genetic informationThis mouse line originates from EUCOMM ES clone EPD0508_3_E02. For further details on the construction of this clone see the page at the IMPC portal. The tm1a mice have been crossed with flp recombinase-expressing mice (EM:05490, C57BL/6NTac-Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics/Ics) to obtain the tm1c allele.
Phenotypic informationHomozygous:
Homozygous mice have not been generated

Heterozygous:
Null
Breeding historyRederived tm1a mice have been crossed with flp recombinase-expressing mice to obtain the line carrying the tm1c allele.
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France
Animals used for archivingheterozygous C57BL/6N

Disease and phenotype information

IMPC phenotypes (gene matching)
  • abnormal optic disk morphology / IMPC
  • increased circulating glucose level / IMPC
  • abnormal auditory brainstem response / IMPC
  • abnormal vitreous body morphology / IMPC
MGI phenotypes (gene matching)
  • abnormal cell death / MGI
  • diluted coat color / MGI
  • abnormal dendritic cell physiology / MGI
  • abnormal macrophage physiology / MGI
  • increased incidence of tumors by chemical induction / MGI
  • decreased platelet serotonin level / MGI
  • abnormal circulating amino acid level / MGI
  • immune system phenotype / MGI
  • increased bleeding time / MGI
  • decreased fibroblast proliferation / MGI
  • increased circulating cysteine level / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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