IMPC phenotypes (gene matching)
B6.129-Siglec1tm1Croc/CrocH
| Status | Available to order |
| EMMA ID | EM:12765 |
| Citation information | RRID:IMSR_EM:12765 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129-Siglec1tm1Croc/CrocH |
| Alternative name | Siglec-1 (CD169) KO mouse |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Siglec1tm1Croc |
| Gene/Transgene symbol | Siglec1 |
Information from provider
| Provider | Paul Crocker |
| Provider affiliation | School of Life Sciences |
| Genetic information | Mouse knock-out model for the Siglec1/CD169 gene. |
| Phenotypic information | Homozygous:No overt phenotype.Heterozygous:No overt phenotype. |
| Breeding history | Backcrossed onto C57BL/6J for at least 8 generations. |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Literature references
- Sialoadhesin-deficient mice exhibit subtle changes in B- and T-cell populations and reduced immunoglobulin M levels.;Oetke Cornelia, Vinson Mary C, Jones Claire, Crocker Paul R, ;2006;Molecular and cellular biology;26;1549-57; 16449664