B6.129S2-Evx2/Hoxd13tm4(cre)Ddu Del(2Hoxd11-Hoxd13)27Ddu/Orl
Status | Available to order |
EMMA ID | EM:01220 |
International strain name | B6.129S2-Evx2/Hoxd13tm4(cre)Ddu Del(2Hoxd11-Hoxd13)27Ddu/Orl |
Alternative name | P1Del |
Strain type | Targeted Mutant Strains : Knock-out |
Allele/Transgene symbol | Del(2Hoxd11-Hoxd13)27Ddu, |
Gene/Transgene symbol | Del(2Hoxd11-Hoxd13)27Ddu |
Information from provider
Provider | Duboule Denis |
Provider affiliation | Laboratoire Moléculaire et Morphogenèse |
Genetic information | Insertion of the Hoxd11Cre transgene between Evx2 and Hoxd13 and deletion of Hoxd13 to Hoxd11 genes by TArgeted MEiotic REcombination (TAMERE). |
Phenotypic information | None. |
Breeding history | Backcross: N=10; Intercross: N=10. |
References |
|
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Brachydactyly-syndactyly, Zhao type / Orphanet_93409
- Brachydactyly type E / Orphanet_93387
- Synpolydactyly type 1 / Orphanet_295195
- Zygodactyly type 3 / Orphanet_295191
- Syndactyly type 5 / Orphanet_93406
Literature references
- A nested deletion approach to generate Cre deleter mice with progressive Hox profiles.;Hérault Yann, Kmita Marie, Sawaya Chadi C, Duboule Denis, ;2002;The International journal of developmental biology;46;185-91; 11902682
Information on how we integrate external resources can be found here
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).