The European Mouse Mutant Archive – EMMA

With more than 8800 mutant mouse strains and a small but increasing number of rat mutant strains available, EMMA is the primary mouse repository in Europe and the third largest non-profit repository worldwide.

Strain Distribution

Access to over 8800 mouse mutants and a couple of tens of rat mutants.

Cryopreservation

EMMA archives your mouse and rat mutants free of charge.

Cryopreservation Protocols

Validated protocols and training videos for mouse embryo and spermatozoa freezing techniques, in vitro fertilisation procedures and embryo transfers.

Strain Collections

Strains originated by large-scale projects archived and distributed by EMMA.

The European Mouse Mutant Archive – EMMA

The European Mouse Mutant Archive – EMMA is the INFRAFRONTIER’s non-profit repository for the collection, archiving (via cryopreservation) and distribution of relevant mutant mouse and rat strains essential for basic biomedical research. The laboratory mouse is the most important mammalian model for studying genetic and multi-factorial diseases in human beings. The comprehensive physical and data resources of EMMA support basic biomedical and preclinical research, and the available research tools and mouse/rat models of human disease offer the opportunity to develop a better understanding of molecular disease mechanisms and may provide the foundation for the development of diagnostic, prognostic and therapeutic strategies. EMMA is a founding member of the Federation of International Mouse Resources (FIMRe).

Up to 500
Shipments per year
8800
Archived strains available
3rd largest
Non-profit mouse repository
50 countries
Users spread over the globe
4.6/5
User satisfaction

The Scientific User Support Team may be addressed bayvar, and its scientifically trained team can offer different levels of support to all interested users. We are continuously working to improve our services, and therefore appreciate to receive feedback based on our users’ experience.

EMMA is supported by the partner institutions, national research programs and by the EC’s Research and Innovation programme Horizon 2020 (H2020-EU.1.4.1.1. Developing new world class research infrastructures).

EMMA Objectives

EMMA’s primary objective is to establish and manage a unified repository for maintaining medically relevant mouse and rat mutants and making them available to the scientific community. Therefore, EMMA archives mutant strains and distributes them to requesting researchers. EMMA also hosts courses in cryopreservation to promote the use and dissemination of frozen embryos and spermatozoa. Dissemination of knowledge is further fostered by a dedicated resource database.

EMMA – Focused on Reduction and Refinement

The European Mouse Mutant Archive (EMMA) is the primary mouse repository in Europe and the third largest of its kind worldwide. It is INFRAFRONTIER´s most important `product´- a smart, openly accessible platform for archiving and distributing thousands of mouse disease models – currently more than 8800.

EMMA Network

The EMMA network is a partnership of several laboratories and other institutions throughout Europe. The current membership includes:

EMMA is open for the incorporation of new members into the current network and detailed guidelines for this process are established. Please pbagnpg hf if you would like to learn more about how to become a member of the network.

The EMMA network is directed by Professor Martin Hrabé de Angelis who heads the Institute of Experimental Genetics and the German Mouse Clinic (GMC) at the Helmholtz Zentrum München.  

Popular Mouse Strains

These are some popular and widely used mouse strains in biomedical research available at the EMMA repository.

Please note: According to the legally binding EMMA conditions users who have received materials from EMMA may not transfer or sell these animals or their progeny to any Third Party outside the recipient institution. If the strains below or any other strain from EMMA is also interesting for your research, please directly order from us.

B6.Cg-Tg(Cdh5-cre/ERT2)1Rha/H

Tamoxifen-inducible Cre deleter specific of vascular endothelial cells.

C57BL/6J-Tg(Pax8-cre/ERT2)CAmat/AmatH

Tamoxifen-inducible Cre recombinase specific of renal tubular epithelia.

B6.129X1-Thtm1(cre)Te/Kieg

Non-inducible Cre recombinase specific of tyrosine hydroxylase (Th) -expressing cells.

Related Pages

Nomenclature Service and Integrated Resources

Overview about the nomenclature services offered by EMMA and the different resources integrated in order to enrich the information related to EMMA strains.

Legal Questions

EMMA repository conditions, MTAs, policy on licensing and use restriction.

Feedback from EMMA users

We are continuously working to improve our services, to better meet your needs.

INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).