INFRAFRONTIER is the European Research Infrastructure for Modelling Human Diseases

We contribute to human health by advancing disease prevention and therapies through appropriate models.

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Cryopreservation Protocols EMMA Cre-driver EUCOMM IMPC Rare Disease COVID-19 Cancer

About INFRAFRONTIER

The INFRAFRONTIER consortium consists of more than 20 leading biomedical research institutes in 15 countries working together to understand basic mammalian gene function and model human diseases.

EMMA

The European Mouse Mutant Archive – EMMA is a non-profit repository for the collection, archiving (via cryopreservation) and distribution of relevant mutant mouse and rat strains essential for basic biomedical research.

Resources and Services

In addition to EMMA, INFRAFRONTIER offers other services like axenic derivation, access to open calls and systemic phenotyping.

Animal Welfare and Ethics

Discover INFRAFRONTIER’s commitment to Animal Welfare and explore the ethical research practices we apply to drive the 3R Principle in animal research.

In the Spotlight

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INFRAPLUS

A Horizon-INFRA-DEV project that aims to expand INFRAFRONTIER’s capacity for human disease modelling, refine its service portfolio by reducing animal usage and developing alternative cellular models, and optimise the use of resources.

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INFRAFRONTIER Cancer Services

Via the canSERV project, INFRAFRONTIER offers access to several cutting-edge cancer services as Open Calls. These services are offered by INFRAFRONTIER partners with world-leading expertise in cancer research and mouse models.

Axenic Service

This service offers the germ-free derivation of user-provided mouse strains for gnotobiotic studies.

Rodent Model Generation

Generation of custom rodent mutant strains using the latest genome-editing technologies by expert laboratories.

COVID-19 Resources and Services

INFRAFRONTIER offers a cutting-edge COVID-19 therapeutics pipeline, a large selection of COVID-19-related strains and emergency archiving services to aid COVID-19 research and minimise the loss of valuable mouse strains.

INFRAFRONTIER and Cancer Research

Browse through EMMA strains associated to more than 50 different cancer types and a list of manually-curated disease models for cancer.

IMPC

INFRAFRONTIER is closely linked to the largest and foremost scientific consortium for mouse phenotyping worldwide – the International Mouse Phenotyping Consortium (IMPC).

Strain Distribution

Prices, Delivery Times, Legal Questions and everything you need to know before ordering mutant strains from us.

Strain Collections

Strains originated by large-scale projects archived and distributed by EMMA.

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INFRAFRONTIER Consortium

Upcoming Trainings & Events

FELASA 2025

02 - 05 June 2025

FELASA

Athens, Greece

Asrar Ali Khan, Auke Börsma, Tania Sorg & Maik Dahlhoff

FEBS 2025 – 49th FEBS Congress

05 - 09 July 2025

FEBS

Istanbul, Turkey

INFRAFRONTIER, INSTRUCT, EU-OPENSCREEN & Euro-BioImaging

Latest News

Scientific Publication December 2, 2024

A Closer Look at the Laboratory Animal Genetic Reporting (LAG-R) Guidelines

Our partners Lydia Teboul and Guillaume Pavlovic are the corresponding authors of the Laboratory Animal Genetic Reporting (LAG-R) framework. Don’t miss their Lab Animal interview, where they discuss its benefits, motivations, and how to accelerate adoption of the recommendations that it presents.

Highlight November 11, 2024

Czech Centre for Phenogenomics Obtains a GLP Certificate

Czech Centre for Phenogenomics (CCP) has obtained a Good Laboratory Practice (GLP) certificate that authorises CCP to perform and provide non-clinical drug safety studies. Studies conducted under the GLP regime are recognised in the registration procedures of medicinal products, and without safety studies, clinical trials of new potential drugs cannot be started.

Highlight November 8, 2024

Revolutionising Research: Cutting-Edge Photoacoustic Imaging

Our colleagues at Czech Centre for Phenogenomics have expanded their capabilities with the VisualSonics Vevo F2 LAZR-X, offering advanced multimodal imaging for oncology, cardiovascular studies, neurobiology, and more. This state-of-the-art photoacoustic ultrasound system will enable cross-functional research with the highest resolution on the market.

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